Experimental and Clinical Pharmacology

Research Output

2015

Pharmacogenetic study of serotonin transporter and 5HT2A genotypes in autism

Najjar, F., Owley, T., Mosconi, M. W., Jacob, S., Hur, K., Guter, S. J., Sweeney, J. A., Gibbons, R. D., Cook, E. H. & Bishop, J. R., Aug 1 2015, In : Journal of child and adolescent psychopharmacology. 25, 6, p. 467-474 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
6 Scopus citations

Phenytoin and fosphenytoin

Conway, J. M., Morita, D. A. & Glauser, T. A., Jan 16 2015, Wyllie's Treatment of Epilepsy: Principles and Practice: Sixth Edition. Wolters Kluwer Health

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer

Xia, S., Kohli, M., Du, M., Dittmar, R. L., Lee, A., Nandy, D., Yuan, T., Guo, Y., Wang, Y., Tschannen, M. R., Worthey, E., Jacob, H., See, W., Kilari, D., Wang, X., Hovey, R. L., Huang, C. C. & Wang, L., Jan 1 2015, In : Oncotarget. 6, 18, p. 16411-16421 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Polymyxins in 2015: It's like Déjà Vu all over again

Pogue, J. M. & Rotschafer, J. C., Jan 1 2015, In : Pharmacotherapy. 35, 1, p. 9-10 2 p.

Research output: Contribution to journalEditorial

Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

Zordoky, B. N. M., Robertson, I. M. & Dyck, J. R. B., Jun 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 6, p. 1155-1177 23 p.

Research output: Contribution to journalReview article

155 Scopus citations

Predicting response to histone deacetylase inhibitors using high-throughput genomics

Geeleher, P., Loboda, A., Lenkala, D., Wang, F., LaCroix, B., Karovic, S., Wang, J., Nebozhyn, M., Chisamore, M., Hardwick, J., Maitland, M. L. & Huang, R. S., Jan 1 2015, In : Journal of the National Cancer Institute. 107, 11, djv247.

Research output: Contribution to journalArticle

9 Scopus citations

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration

Liu, P., Reed, M. N., Kotilinek, L. A., Grant, M. K. O., Forster, C. L., Qiang, W., Shapiro, S. L., Reichl, J. H., Chiang, A. C. A., Jankowsky, J. L., Wilmot, C. M., Cleary, J. P., Zahs, K. R. & Ashe, K. H., Jun 23 2015, In : Cell reports. 11, 11, p. 1760-1771 12 p.

Research output: Contribution to journalArticle

77 Scopus citations

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing

Kowalsky, C. A., Faber, M. S., Nath, A., Dann, H. E., Kelly, V. W., Liu, L., Shanker, P., Wagner, E. K., Maynard, J. A., Chan, C. & Whitehead, T. A., Oct 30 2015, In : Journal of Biological Chemistry. 290, 44, p. 26457-26470 14 p.

Research output: Contribution to journalArticle

33 Scopus citations

Referential processing in the human brain: An Event-Related Potential (ERP) study

Barkley, C. M., Kluender, R. & Kutas, M., Dec 10 2015, In : Brain Research. 1629, p. 143-159 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Regressing to Prior Response Preference after Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings from the B-SNIP Study

Hill, S. K., Reilly, J. L., Ragozzino, M. E., Rubin, L. H., Bishop, J. R., Gur, R. C., Gershon, E. S., Tamminga, C. A., Pearlson, G. D., Keshavan, M. S., Keefe, R. S. E. & Sweeney, J. A., Jul 1 2015, In : Schizophrenia bulletin. 41, 4, p. 940-950 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Research fellowship programs as a pathway for training independent clinical pharmacy scientists

Mueller, E. W., Bishop, J. R., Kanaan, A. O., Kiser, T. H., Phan, H. & Yang, K. Y., Mar 1 2015, In : Pharmacotherapy. 35, 3, p. e13-e19

Research output: Contribution to journalReview article

6 Scopus citations

Single nucleotide polymorphisms (SNPs) Associated with Acute Rejection in European American Kidney Transplant Recipients: a Genome Wide Association Study (GWAS)

Israni, A., Dorr, C., Miller, M., Schladt, D., Sanghavi, K., Muthusamy, A., Remmel, R., Guan, W., Wu, B. & Oetting, W., 2015.

Research output: Contribution to conferencePaper

SNP genotyping using TaqMan® technology: The CYP2D6∗17 assay conundrum

Gaedigk, A., Freeman, N., Hartshorne, T., Riffel, A. K., Irwin, D., Bishop, J. R., Stein, M. A., Newcorn, J. H., Jaime, L. K. M., Cherner, M. & Leeder, J. S., Mar 19 2015, In : Scientific reports. 5, 9257.

Research output: Contribution to journalArticle

16 Scopus citations
7 Scopus citations

Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly

Segrest, J. P., Jones, M. K., Catte, A., Manchekar, M., Datta, G., Zhang, L., Zhang, R., Li, L., Patterson, J. C., Palgunachari, M. N., Oram, J. F. & Ren, G., Jul 9 2015, In : Structure. 23, 7, p. 1214-1226 13 p., 3193.

Research output: Contribution to journalArticle

23 Scopus citations

Telephone-adapted mindfulness-based stress reduction (tMBSR) for patients awaiting kidney transplantation: Trial design, rationale and feasibility

Reilly-Spong, M., Reibel, D., Pearson, T., Koppa, P. & Gross, C. R., May 1 2015, In : Contemporary Clinical Trials. 42, p. 169-184 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

The mediating effect of prefrontal asymmetry on the relationship between the COMT Val158Met SNP and trait consummatory positive affect

Katz, A. C., Sarapas, C., Bishop, J. R., Patel, S. R. & Shankman, S. A., Jul 4 2015, In : Cognition and Emotion. 29, 5, p. 867-881 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia

Abner, E. L., Schmitt, F. A., Nelson, P. T., Lou, W., Wan, L., Gauriglia, R., Dodge, H. H., Woltjer, R. L., Yu, L., Bennett, D. A., Schneider, J. A., Chen, R., Masaki, K., Katz, M. J., Lipton, R. B., Dickson, D. W., Lim, K. O., Hemmy, L. S., Cairns, N. J., Grant, E. & 4 others, Tyas, S. L., Xiong, C., Fardo, D. W. & Kryscio, R. J., Mar 2015, In : Design Studies. 1, 2015, p. 56-73 18 p.

Research output: Contribution to journalArticle

Third International Congress on Epilepsy, Brain and Mind: Part 1

Korczyn, A. D., Schachter, S. C., Amlerova, J., Bialer, M., van Emde Boas, W., Brázdil, M., Brodtkorb, E., Engel, J., Gotman, J., Komárek, V., Leppik, I. E., Marusic, P., Meletti, S., Metternich, B., Moulin, C. J. A., Muhlert, N., Mula, M., Nakken, K. O., Picard, F., Schulze-Bonhage, A. & 4 others, Theodore, W., Wolf, P., Zeman, A. & Rektor, I., Sep 1 2015, In : Epilepsy and Behavior. 50, p. 116-137 22 p.

Research output: Contribution to journalReview article

9 Scopus citations

Urinary bile acids as biomarkers for liver diseases I. stability of the baseline profile in healthy subjects

Bathena, S. P. R., Thakare, R., Gautam, N., Mukherjee, S., Olivera, M., Meza, J. & Alnouti, Y., Feb 1 2015, In : Toxicological Sciences. 143, 2, p. 296-307 12 p., kfu227.

Research output: Contribution to journalArticle

25 Scopus citations

Urinary bile acids as biomarkers for liver diseases II. signature profiles in patients

Bathena, S. P. R., Thakare, R., Gautam, N., Mukherjee, S., Olivera, M., Meza, J. & Alnouti, Y., Feb 1 2015, In : Toxicological Sciences. 143, 2, p. 308-318 11 p., kfu228.

Research output: Contribution to journalArticle

19 Scopus citations
3 Scopus citations

Using automatic speech recognition to assess spoken responses to cognitive tests of semantic verbal fluency

Pakhomov, S. V. S., Marino, S. E., Banks, S. & Bernick, C., Dec 1 2015, In : Speech Communication. 75, p. 14-26 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies

Siegel, R. A., Kapoor, M., Cheryala, N., Georg, G. I. & Cloyd, J. C., Aug 1 2015, In : Epilepsy and Behavior. 49, p. 347-350 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

A 16-month community-based intervention to increase aspirin use for primary prevention of cardiovascular disease

Oldenburg, N. C., Duval, S., Luepker, R. V., Finnegan, J. R., LaMarre, H., Peterson, K. A., Zantek, N. D., Jacobs, G., Straka, R. J., Miller, K. H. & Hirsch, A. T., May 2014, In : Preventing Chronic Disease. 11, 5, 130378.

Research output: Contribution to journalArticle

8 Scopus citations

A DPYD variant (y186c) specific to individuals of african descent in a patient with life-threatening 5-fu toxic effects: Potential for an individualized medicine approach

Saif, M. W., Lee, A. M., Offer, S. M., McConnell, K., Relias, V. & Diasio, R. B., Jan 2014, In : Mayo Clinic Proceedings. 89, 1, p. 131-136 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Age-related physiologic changes, risk of adverse effects guide your prescribing

Hong, I. S. & Bishop, J. R., Jan 1 2014, In : Current Psychiatry. 13, 10, p. 36-52 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alternative viewpoint: Preparation for residency

Knapp, K. K., Mészáros, K., Goldsmith, P. C., McCarter, G. C., Hester, E. K., McBane, S. E., Bottorff, M. B., Carnes, T. A., Dell, K., Gonyeau, M. J., Greco, A. J., McConnell, K. J., Skaar, D. J., Splinter, M. Y. & Trujillo, T. C., Aug 2014, In : Pharmacotherapy. 34, 8, p. e157-e158

Research output: Contribution to journalComment/debate

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation

Zordoky, B. N. M., Nagendran, J., Pulinilkunnil, T., Kienesberger, P. C., Masson, G., Waller, T. J., Kemp, B. E., Steinberg, G. R. & Dyck, J. R. B., Aug 15 2014, In : Circulation research. 115, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers

Agarwal, S. K., Kriel, R. L., Cloyd, J. C., Coles, L. D., Scherkenbach, L. A., Tobin, M. H. & Krach, L. E., Jan 1 2014, In : Journal of Child Neurology. 30, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Are individual differences in appetitive and defensive motivation related? A psychophysiological examination in two samples

Sarapas, C., Katz, A. C., Nelson, B. D., Campbell, M. L., Bishop, J. R., Robison-Andrew, E. J., Altman, S. E., Gorka, S. M. & Shankman, S. A., May 2014, In : Cognition and Emotion. 28, 4, p. 636-655 20 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association of variants in DRD2 and GRM3 with motor and cognitive function in first-episode psychosis

Lencer, R., Bishop, J. R., Harris, M. S. H., Reilly, J. L., Patel, S., Kittles, R., Prasad, K. M., Nimgaonkar, V. L., Keshavan, M. S. & Sweeney, J. A., Jun 2014, In : European Archives of Psychiatry and Clinical Neuroscience. 264, 4, p. 345-355 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Association study of the let-7 miRNA-complementary site variant in the 3′ untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 clinical trial)

Sha, D., Lee, A. M., Shi, Q., Alberts, S. R., Sargent, D. J., Sinicrope, F. A. & Diasio, R. B., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3319-3327 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design

Wang, T., Baron, K., Zhong, W., Brundage, R. & Elmquist, W., Mar 2014, In : Pharmaceutical research. 31, 3, p. 649-659 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cell permeable vanX inhibitors as vancomycin re-sensitizing agents

Muthyala, R., Rastogi, N., Shin, W. S., Peterson, M. L. & Sham, Y. Y., Jun 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 11, p. 2535-2538 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations

Cholesterol as a causative factor in Alzheimer's disease: A debatable hypothesis

Wood, W. G., Li, L., Müller, W. E. & Eckert, G. P., May 2014, In : Journal of Neurochemistry. 129, 4, p. 559-572 14 p.

Research output: Contribution to journalReview article

99 Scopus citations

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

Geeleher, P., Cox, N. J. & Huang, R. S., Mar 3 2014, In : Genome biology. 15, 3, R47.

Research output: Contribution to journalArticle

111 Scopus citations

Clinically Relevant Variants - Identifying, Collecting, Interpreting, and Disseminating: The 2013 Annual Scientific Meeting of the Human Genome Variation Society

Stanley, C. M., Sunyaev, S. R., Greenblatt, M. S. & Oetting, W. S., Apr 2014, In : Human mutation. 35, 4, p. 505-510 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal

Chapman, S. A., Irwin, E. D., Abou-Karam, N. M., Rupnow, N. M., Hutson, K. E., Vespa, J. & Roach, R. M., Apr 15 2014, In : World Journal of Emergency Surgery. 9, 1, 27.

Research output: Contribution to journalArticle

10 Scopus citations

Competing endogenous RNAs (ceRNAs): New entrants to the intricacies of gene regulation

Kartha, R. V. & Subramanian, S., Jan 1 2014, In : Frontiers in Genetics. 5, JAN, Article 8.

Research output: Contribution to journalReview article

169 Scopus citations

Disease and drug effects on internally-generated and externally-elicited responses in first episode schizophrenia and psychotic bipolar disorder

Keedy, S. K., Bishop, J. R., Weiden, P. J., Sweeney, J. A., Rosen, C., Marvin, R. & Reilly, J. L., Oct 1 2014, In : Schizophrenia Research. 159, 1, p. 101-106 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder

Stein, M. A., Waldman, I., Newcorn, J., Bishop, J., Kittles, R. & Cook, E. H., Jun 1 2014, In : Journal of child and adolescent psychopharmacology. 24, 5, p. 238-244 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147)

Lee, A. M., Shi, Q., Pavey, E., Alberts, S. R., Sargent, D. J., Sinicrope, F. A., Berenberg, J. L., Goldberg, R. M. & Diasio, R. B., Dec 1 2014, In : Journal of the National Cancer Institute. 106, 12, dju298.

Research output: Contribution to journalArticle

74 Scopus citations

Educational outcomes necessary to enter pharmacy residency training

Hester, E. K., McBane, S. E., Bottorff, M. B., Carnes, T. A., Dell, K., Gonyeau, M. J., Greco, A. J., McConnell, K. J., Skaar, D. J., Splinter, M. Y. & Trujillo, T. C., Apr 2014, In : Pharmacotherapy. 34, 4, p. e22-e25

Research output: Contribution to journalArticle

6 Scopus citations

Emotional well-being of living kidney donors: Findings from the RELIVE study

Jowsey, S. G., Jacobs, C., Gross, C. R., Hong, B. A., Messersmith, E. E., Gillespie, B. W., Beebe, T. J., Kew, C., Matas, A., Yusen, R. D., Hill-Callahan, M., Odim, J. & Taler, S. J., Nov 1 2014, In : American Journal of Transplantation. 14, 11, p. 2535-2544 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Encapsulation in nanoparticles improves anti-cancer efficacy of carboplatin

Sadhukha, T. & Prabha, S., Aug 2014, In : AAPS PharmSciTech. 15, 4, p. 1029-1038 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Ethnic and genetic factors in methadone pharmacokinetics: A population pharmacokinetic study

Bart, G., Lenz, S., Straka, R. J. & Brundage, R., Dec 1 2014, In : Drug and alcohol dependence. 145, p. 185-193 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention

Nicol, M. R., Fedoriw, Y., Mathews, M., Prince, H. M. A., Patterson, K. B., Geller, E., Mollan, K., Mathews, S., Kroetz, D. L. & Kashuba, A. D. M., May 2014, In : Journal of Clinical Pharmacology. 54, 5, p. 574-583 10 p.

Research output: Contribution to journalArticle

29 Scopus citations