Experimental and Clinical Pharmacology

Research Output

2016
Open Access
8 Scopus citations

Common genetic variation in CYP17A1 and response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer

Binder, M., Zhang, B. Y., Hillman, D. W., Kohli, R., Kohli, T., Lee, A. & Kohli, M., Jul 2016, In : International journal of molecular sciences. 17, 7, 1097.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Consistency in large pharmacogenomic studies

Geeleher, P., Gamazon, E. R., Seoighe, C., Cox, N. J. & Huang, R. S., Nov 30 2016, In : Nature. 540, 7631, p. E1-E2

Research output: Contribution to journalShort survey

Open Access
19 Scopus citations

Critical evaluation of ceftolozane–tazobactam for complicated urinary tract and intra-abdominal infections

Giancola, S. E., Mahoney, M. V., Bias, T. E. & Hirsch, E. B., May 19 2016, In : Therapeutics and Clinical Risk Management. 12, p. 787-797 11 p.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations

Deconstructing tolerance with clobazam

Gidal, B. E., Wechsler, R. T., Sankar, R., Montouris, G. D., White, H. S., Cloyd, J. C., Kane, M. C., Peng, G., Tworek, D. M., Shen, V. & Isojarvi, J., Oct 25 2016, In : Neurology. 87, 17, p. 1806-1812 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Development of an interprofessional and interdisciplinary collaborative research practice for clinical faculty

Hager, K., St Hill, C., Prunuske, J., Swanoski, M., Anderson, G. & Lutfiyya, M. N., Mar 3 2016, In : Journal of interprofessional care. 30, 2, p. 265-267 3 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Discrepancy in vancomycin AUC/MIC ratio targeted attainment based upon the susceptibility testing in Staphylococcus aureus

Eum, S., Bergsbaken, R. L., Harvey, C. L., Warren, J. B. & Rotschafer, J. C., Dec 2016, In : Antibiotics. 5, 4, 34.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Entrustable professional activities for pharmacy practice

Pittenger, A. L., Chapman, S. A., Frail, C. K., Moon, J. Y., Undeberg, M. R. & Orzoff, J. H., Jan 1 2016, In : American journal of pharmaceutical education. 80, 4, 57.

Research output: Contribution to journalArticle

33 Scopus citations
Open Access
9 Scopus citations
Open Access
62 Scopus citations

Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles

Oetting, W. S., Schladt, D. P., Guan, W., Miller, M. B., Remmel, R. P., Dorr, C., Sanghavi, K., Mannon, R. B., Herrera, B., Matas, A. J., Salomon, D. R., Kwok, P. Y., Keating, B. J., Israni, A. K. & Jacobson, P. A., Feb 1 2016, In : American Journal of Transplantation. 16, 2, p. 574-582 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Glycoengineered mesenchymal stem cells as an enabling platform for two-step targeting of solid tumors

Layek, B., Sadhukha, T. & Prabha, S., May 1 2016, In : Biomaterials. 88, p. 97-109 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Gram-positive resistance-clinical implications

Rotschafer, J. C., Ullman, M. A. & Mitropoulos, I., Apr 19 2016, MRSA: Second Edition. CRC Press, p. 188-208 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

High expression of MIR-532-5p, a tumor suppressor, leads to better prognosis in ovarian cancer both in vivo and in vitro

Wang, F., Chang, J. T. H., Kao, C. J. & Huang, R. S., May 2016, In : Molecular Cancer Therapeutics. 15, 5, p. 1123-1131 9 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

High-Risk Pharmacogenetic (PGx) Variants in Kidney Transplant (tx) Recipients

Berglund, D., Schladt, D., Sanghavi, K., Guan, W., Wu, B., Dorr, C., Remmel, R., Mannon, R., Matas, A. & Oetting, W., 2016, p. 321. 1 p.

Research output: Contribution to conferencePaper

Identification of MicroRNAs as breast cancer prognosis markers through the cancer genome atlas

Chang, J. T. H., Wang, F., Chapin, W. & Huang, R. S., Dec 2016, In : PloS one. 11, 12, e0168284.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Impact of hyperglycemia on outcomes of patients with Pseudomonas aeruginosa bacteremia

Patel, T. S., Cottreau, J. M., Hirsch, E. B. & Tam, V. H., Feb 1 2016, In : Diagnostic Microbiology and Infectious Disease. 84, 2, p. 155-158 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Intravenous topiramate: Pharmacokinetics in dogs with naturally occurring epilepsy

Vuu, I., Coles, L. D., Maglalang, P., Leppik, I. E., Worrell, G., Crepeau, D., Mishra, U., Cloyd, J. C. & Patterson, E. E., Dec 5 2016, In : Frontiers in Veterinary Science. 3, DEC, 107.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Local epidermal growth factor receptor signaling mediates the systemic pathogenic effects of staphylococcus aureus toxic shock syndrome

Breshears, L. M., Gillman, A. N., Stach, C. S., Schlievert, P. M. & Peterson, M. L., Jul 2016, In : PloS one. 11, 7, e0158969.

Research output: Contribution to journalArticle

Lymphoblastoid cell lines as a tool to study inter-individual differences in the response to glucose

Michael, A. G., Vidhya, R. R., Siquan, C., Dingcai, C., Xiaoyu, G., Patricia, A. C., Stephanie Huang, R., Andrew, D. P., Rama, N., Jalees, R. & Timothy, S. K., Aug 2016, In : PloS one. 11, 8, e0160504.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Metabolic Labeling with an Alkyne-modified Isoprenoid Analog Facilitates Imaging and Quantification of the Prenylome in Cells

Palsuledesai, C. C., Ochocki, J. D., Kuhns, M. M., Wang, Y. C., Warmka, J. K., Chernick, D. S., Wattenberg, E. V., Li, L., Arriaga, E. A. & Distefano, M. D., Oct 21 2016, In : ACS Chemical Biology. 11, 10, p. 2820-2828 9 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Nanoparticle-Mediated Photodynamic Therapy for Mixed Biofilms

Usacheva, M., Layek, B., Rahman Nirzhor, S. S. & Prabha, S., Jan 1 2016, In : Journal of Nanomaterials. 2016, 4752894.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Non-weight-based enoxaparin dosing subtherapeutic in trauma patients

Chapman, S. A., Irwin, E. D., Reicks, P. & Beilman, G. J., Mar 1 2016, In : Journal of Surgical Research. 201, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Operational Characteristics of Linear Concentration-QT Models for Assessing QTc Interval in the Thorough QT and Phase I Clinical Studies

Garnett, C., Needleman, K., Liu, J., Brundage, R. & Wang, Y., Aug 1 2016, In : Clinical pharmacology and therapeutics. p. 170-178 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pathogenicity Interpretation in the Age of Precision Medicine: The 2015 Annual Scientific Meeting of the Human Genome Variation Society

Oetting, W. S., Brenner, S. E., Brookes, A. J., Greenblatt, M. S., Hart, R. K., Karchin, R., Sunyaev, S. R. & Taschner, P. E., Apr 1 2016, In : Human mutation. 37, 4, p. 406-411 6 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning

Sanghavi, K. J., Wiseman, A., Kirstein, M. N., Cao, Q., Brundage, R., Jensen, K., Rogosheske, J., Kurtzweil, A., Long-Boyle, J., Wagner, J. E., Warlick, E. D., Brunstein, C. G., Weisdorf, D. J. & Jacobson, P. A., Sep 1 2016, In : Translational Research. 175, p. 103-115.e4

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Pharmacogenetic Allele Nomenclature: International Workgroup Recommendations for Test Result Reporting

Kalman, L. V., Agúndez, J. A. G., Appell, M. L., Black, J. L., Bell, G. C., Boukouvala, S., Bruckner, C., Bruford, E., Caudle, K., Coulthard, S. A., Daly, A. K., Del Tredici, A. L., Den Dunnen, J. T., Drozda, K., Everts, R. E., Flockhart, D., Freimuth, R. R., Gaedigk, A., Hachad, H., Hartshorne, T. & 26 others, Ingelman-Sundberg, M., Klein, T. E., Lauschke, V. M., Maglott, D. R., McLeod, H. L., McMillin, G. A., Meyer, U. A., Müller, D. J., Nickerson, D. A., Oetting, W. S., Pacanowski, M., Pratt, V. M., Relling, M. V., Roberts, A., Rubinstein, W. S., Sangkuhl, K., Schwab, M., Scott, S. A., Sim, S. C., Thirumaran, R. K., Toji, L. H., Tyndale, R. F., Van Schaik, R. H. N., Whirl-Carrillo, M., Yeo, K. T. J. & Zanger, U. M., Feb 1 2016, In : Clinical pharmacology and therapeutics. 99, 2, p. 172-185 14 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Pharmacogenetic tests for antipsychotic medications: Clinical implications and considerations

Eum, S., Lee, A. M. & Bishop, J. R., Jan 1 2016, In : Dialogues in Clinical Neuroscience. 18, 3, p. 323-337 15 p.

Research output: Contribution to journalArticle

15 Scopus citations
Open Access
3 Scopus citations
Open Access
3 Scopus citations

Prodrug strategy: An effective tool in drug delivery and targeting

Layek, B., Paul, S. & Singh, J., Nov 3 2016, Bio-Targets and Drug Delivery Approaches. CRC Press, p. 77-111 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Progress against Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach to improving whole-cell gram-negative activity

Takrouri, K., Cooper, H. D., Spaulding, A., Zucchi, P., Koleva, B., Cleary, D. C., Tear, W., Beuning, P. J., Hirsch, E. B. & Aggen, J. B., Jun 10 2016, In : ACS Infectious Diseases. 2, 6, p. 405-426 22 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prospective studies of infectious mononucleosis in university students

Grimm, J. M., Schmeling, D. O., Dunmire, S. K., Knight, J. A., Mullan, B. D., Ed, J. A., Brundage, R. C., Hogquist, K. A. & Balfour, H. H., Aug 12 2016, In : Clinical and Translational Immunology. 5, 8, e94.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Protocol for examining human vaginal epithelial cell signaling in response to staphylococcal superantigens

Breshears, L. M. & Peterson, M. L., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 149-158 10 p. (Methods in Molecular Biology; vol. 1396).

Research output: Chapter in Book/Report/Conference proceedingChapter

Randomized, blinded trial of vitamin D 3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS)

Shapiro, A. C., Adlis, S. A., Robien, K., Kirstein, M. N., Liang, S., Richter, S. A. & Lerner, R. E., Feb 1 2016, In : Breast Cancer Research and Treatment. 155, 3, p. 501-512 12 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Sex and Diagnosis-Specific Associations between DNA Methylation of the Oxytocin Receptor Gene with Emotion Processing and Temporal-Limbic and Prefrontal Brain Volumes in Psychotic Disorders

Rubin, L. H., Connelly, J. J., Reilly, J. L., Carter, C. S., Drogos, L. L., Pournajafi-Nazarloo, H., Ruocco, A. C., Keedy, S. K., Matthew, I., Tandon, N., Pearlson, G. D., Clementz, B. A., Tamminga, C. A., Gershon, E. S., Keshavan, M. S., Bishop, J. R. & Sweeney, J. A., Feb 1 2016, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 1, 2, p. 141-151 11 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations
Open Access
6 Scopus citations

Susceptibility of multidrug-resistant gram-negative urine isolates to oral antibiotics

Hirsch, E. B., Zucchi, P. C., Chen, A., Raux, B. R., Kirby, J. E., McCoy, C. & Eliopoulos, G. M., May 2016, In : Antimicrobial agents and chemotherapy. 60, 5, p. 3138-3140 3 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

The Acinetobacter baumannii two-component system aders regulates genes required for multidrug efflux, biofilm formation, and virulence in a strain-specific manner

Richmond, G. E., Evans, L. P., Anderson, M. J., Wand, M. E., Bonney, L. C., Ivens, A., Chua, K. L., Webber, M. A., Mark Sutton, J., Peterson, M. L. & Piddock, L. J. V., Apr 19 2016, In : mBio. 7, 2, e00430-16.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

Zordoky, B. N., Radin, M. J., Heller, L., Tobias, A., Matise, I., Apple, F. S., Mccune, S. A. & Sharkey, L. C., Dec 1 2016, In : Cardio-Oncology. 2, 1

Research output: Contribution to journalArticle

Open Access

Use of an automated mobile application to assess effects of nicotine withdrawal on verbal fluency: A pilot study

Pakhomov, S. V., Teeple, W., Mills, A. M. & Kotlyar, M., Oct 1 2016, In : Experimental and Clinical Psychopharmacology. 24, 5, p. 341-347 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients

Morrison, G., Lenkala, D., LaCroix, B., Ziliak, D., Abramson, V., Morrow, P. K., Forero, A., Van Poznak, C., Rugo, H. S., Nanda, R., O'Donnell, P. H. & Huang, R. S., Jan 1 2016, In : Oncotarget. 7, 25, p. 38359-38366 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Vascular biomarkers to predict response to exercise in Alzheimer's disease: The study protocol

Li, D., Thomas, R. M., Tsai, M. Y., Li, L., Vock, D. M., Greimel, S. & Yu, F., Dec 1 2016, In : BMJ open. 6, 12, e011054.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Well-Being and Self-Assessment of Change: Secondary Analysis of an RCT That Demonstrated Benefit of Inhaled Lavender and Sleep Hygiene in College Students with Sleep Problems

Lillehei, A. S., Halcón, L., Gross, C. R., Savik, K. & Reis, R., Nov 1 2016, In : Explore: The Journal of Science and Healing. 12, 6, p. 427-435 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density

Rudolph, A., Fasching, P. A., Behrens, S., Eilber, U., Bolla, M. K., Wang, Q., Thompson, D., Czene, K., Brand, J. S., Li, J., Scott, C., Pankratz, V. S., Brandt, K., Hallberg, E., Olson, J. E., Lee, A., Beckmann, M. W., Ekici, A. B., Haeberle, L., Maskarinec, G. & 20 others, Le Marchand, L., Schumacher, F., Milne, R. L., Knight, J. A., Apicella, C., Southey, M. C., Kapuscinski, M. K., Hopper, J. L., Andrulis, I. L., Giles, G. G., Haiman, C. A., Khaw, K. T., Luben, R., Hall, P., Pharoah, P. D. P., Couch, F. J., Easton, D. F., dos-Santos-Silva, I., Vachon, C. & Chang-Claude, J., Aug 16 2015, In : Breast Cancer Research. 17, 1, 110.

Research output: Contribution to journalArticle

8 Scopus citations

Activity of fosfomycin and comparison of several susceptibility testing methods against contemporary urine isolates

Hirsch, E. B., Raux, B. R., Zucchi, P. C., Kim, Y., McCoy, C., Kirby, J. E., Wright, S. B. & Eliopoulos, G. M., Dec 1 2015, In : International Journal of Antimicrobial Agents. 46, 6, p. 642-647 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network

Hidalgo, B., Aslibekyan, S., Wiener, H. W., Irvin, M. R., Straka, R. J., Borecki, I. B., Tiwari, H. K., Tsai, M. Y., Hopkins, P. N., Ordovas, J. M. & Arnett, D. K., Sep 23 2015, In : Pharmacogenetics and genomics. 25, 10, p. 511-514 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

A major human oral lysophosphatidic acid species, LPA 18:1, regulates novel genes in human gingival fibroblasts

Cerutis, D. R., Weston, M. D., Alnouti, Y., Bathena, S. P., Nunn, M. E., Ogunleye, A. O., McVaney, T. P., Headen, K. V. & Miyamoto, T., May 1 2015, In : Journal of periodontology. 86, 5, p. 713-725 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism

Sung, M. M., Zordoky, B. N., Bujak, A. L., Lally, J. S. V., Fung, D., Young, M. E., Horman, S., Miller, E. J., Light, P. E., Kemp, B. E., Steinberg, G. R. & Dyck, J. R. B., Jul 15 2015, In : Cardiovascular Research. 107, 2, p. 235-245 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Angiotensin-converting enzyme inhibitor induced angioedema: predictors of mechanical ventilation and treatment approaches

Baumgartner, L. J., Morris, A. A. & Chapman, S. A., Sep 28 2015, In : Intensive Care Medicine. 41, 12, p. 2233-2234 2 p.

Research output: Contribution to journalLetter

3 Scopus citations