Experimental and Clinical Pharmacology

Research Output

2019

Consensus Clinical Decision-Making Factors Driving Anticoagulation in Atrial Fibrillation

King, P. K., Fosnight, S. M. & Bishop, J. R., Oct 1 2019, In : American Journal of Cardiology. 124, 7, p. 1038-1043 6 p.

Research output: Contribution to journalArticle

Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery

Layek, B., Rahman Nirzhor, S. S., Rathi, S., Kandimalla, K. K., Wiedmann, T. S. & Prabha, S., Feb 1 2019, In : AAPS PharmSciTech. 20, 2, 58.

Research output: Contribution to journalArticle

2 Scopus citations

Development and validation of a sensitive LC-MS/MS method for the estimation of scopolamine in human serum

Swaminathan, S. K., Fisher, J., Brogden, N. K. & Kandimalla, K. K., Feb 5 2019, In : Journal of Pharmaceutical and Biomedical Analysis. 164, p. 41-46 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes

Nath, A., Lau, E. Y. T., Lee, A. M., Geeleher, P., Cho, W. C. S. & Huang, R. S., Oct 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22020-22029 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Does the beta-lactam matter? Nafcillin versus cefazolin for methicillin-susceptible staphylococcus aureus bloodstream infections

Burrelli, C. C., Broadbent, E. K., Margulis, A., Snyder, G. M., Gold, H. S., McCoy, C., Mahoney, M. V. & Hirsch, E. B., Apr 1 2019, In : Chemotherapy. 63, 6, p. 345-351 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study

EpiBioS4Rx Study Group Investigators, Mar 2019, In : Neurobiology of Disease. 123, p. 115-121 7 p.

Research output: Contribution to journalReview article

Open Access
10 Scopus citations

Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers

Denlinger-Apte, R. L., Kotlyar, M., Koopmeiners, J. S., Tidey, J. W., Luo, X., Benowitz, N. L., Jensen, J. A., Ikuemonisan, J. O., Pacek, L. R., Smith, T. T., Vandrey, R., Donny, E. C. & Hatsukami, D. K., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S63-S72

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation

Li, F., Upadhyaya, N. M., Sperschneider, J., Matny, O., Nguyen-Phuc, H., Mago, R., Raley, C., Miller, M. E., Silverstein, K. A. T., Henningsen, E., Hirsch, C. D., Visser, B., Pretorius, Z. A., Steffenson, B. J., Schwessinger, B., Dodds, P. N. & Figueroa, M., Dec 1 2019, In : Nature communications. 10, 1, 5068.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Engineered mesenchymal stem cells for targeting solid tumors: Therapeutic potential beyond regenerative therapy

Cheng, S., Nethi, S. K., Rathi, S., Layek, B. & Prabha, S., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 2, p. 231-241 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy

Birnbaum, A. K., Karanam, A., Marino, S. E., Barkley, C. M., Remmel, R. P., Roslawski, M., Gramling-Aden, M. & Leppik, I. E., Jan 1 2019, In : Epilepsia. 60, 8, p. 1586-1592 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Baruffaldi, F., Raleigh, M. D., King, S. J., Roslawski, M. J., Birnbaum, A. K., Hassler, C., Carroll, F. I., Runyon, S. P., Winston, S., Pentel, P. R. & Pravetoni, M., Jun 3 2019, In : Molecular pharmaceutics. 16, 6, p. 2364-2375 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion

Alharbi, A. F., Kratzke, R. A., D’Cunha, J., Maddaus, M. A., Sanghavi, K. & Kirstein, M. N., Feb 5 2019, In : Cancer chemotherapy and pharmacology. 83, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle

Open Access

Generic drug products in paediatrics: Where are the data?

Illamola, S. M., Birnbaum, A. K. & Sherwin, C. M., Jan 1 2019, In : British Journal of Clinical Pharmacology. 85, 9, p. 1871-1873 3 p.

Research output: Contribution to journalEditorial

Open Access

Genetic variants associated with immunosuppressant pharmacokinetics and adverse effects in the DeKAF genomics genome-wide association studies

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Van Setten, J., Keating, B. J., Iklé, D., Remmel, R. P., Dorr, C. R., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Jun 1 2019, In : Transplantation. 103, 6, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

How High Can Patients Get on CBD?

Birnbaum, A., Nov 1 2019, In : Epilepsy Currents. 19, 6, p. 382-384 3 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Human cerebrospinal fluid 6E10- immunoreactive protein species contain amyloid precursor protein fragments

Grant, M. K. O., Handoko, M., Rozga, M., Brinkmalm, G., Portelius, E., Blennow, K., Ashe, K. H., Zahs, K. R. & Liu, P., Feb 2019, In : PloS one. 14, 2, e0212815.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
3 Scopus citations

Improving payload capacity and anti-tumor efficacy of mesenchymal stem cells using tat peptide functionalized polymeric nanoparticles

Moku, G., Layek, B., Trautman, L., Putnam, S., Panyam, J. & Prabha, S., Apr 2019, In : Cancers. 11, 4, 491.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Interprofessional education within a pilot HIV-care elective course

Pittenger, A. L., Goodroad, B., Nicol, M., Durgin, E. N., Eveland, L., Kaiser, R., Benbenek, M., Benson, N. R. & Rybicki, S., Dec 2019, In : American journal of pharmaceutical education. 83, 10, p. 2053-2058 6 p., 7402.

Research output: Contribution to journalArticle

Intranasal coadministration of a diazepam prodrug with a converting enzyme results in rapid absorption of diazepam in rats

Rautiola, D., Maglalang, P. D., Cheryala, N., Nelson, K. M., Georg, G. I., Fine, J. M., Svitak, A. L., Faltesek, K. A., Hanson, L. R., Mishra, U., Coles, L. D., Cloyd, J. C. & Siegel, R. A., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 796-805 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Learning a Low-Rank Tensor of Pharmacogenomic Multi-relations from Biomedical Networks

Li, Z., Zhang, W., Huang, R. S. & Kuang, R., Nov 2019, Proceedings - 19th IEEE International Conference on Data Mining, ICDM 2019. Wang, J., Shim, K. & Wu, X. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 409-418 10 p. 8970888. (Proceedings - IEEE International Conference on Data Mining, ICDM; vol. 2019-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lessons from the Established Status Epilepticus Treatment Trial

Cock, H. R., Coles, L. D., Elm, J., Silbergleit, R., Chamberlain, J. M., Cloyd, J. C., Fountain, N., Shinnar, S., Lowenstein, D., Conwit, R., Bleck, T. P. & Kapur, J., Jan 1 2019, (Accepted/In press) In : Epilepsy and Behavior. 106296.

Research output: Contribution to journalArticle

2 Scopus citations

Leveraging the cardio-protective and anticancer properties of resveratrol in cardio-oncology

Abdelgawad, I. Y., Grant, M. K. O. & Zordoky, B. N., Mar 2019, In : Nutrients. 11, 3, 627.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations
Open Access
2 Scopus citations

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

on behalf of the IGNITE Network, Oct 1 2019, In : Genetics in Medicine. 21, 10, p. 2255-2263 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
Open Access
2 Scopus citations

Neurochemical abnormalities in patients with type 1 Gaucher disease on standard of care therapy

Kartha, R. V., Joers, J., Terluk, M. R., Travis, A., Rudser, K., Tuite, P. J., Weinreb, N. J., Jarnes, J. R., Cloyd, J. C. & Öz, G., Jan 1 2019, (Accepted/In press) In : Journal of Inherited Metabolic Disease.

Research output: Contribution to journalArticle

1 Scopus citations

NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis

Alliey-Rodriguez, N., Grey, T. A., Shafee, R., Asif, H., Lutz, O., Bolo, N. R., Padmanabhan, J., Tandon, N., Klinger, M., Reis, K., Spring, J., Coppes, L., Zeng, V., Hegde, R. R., Hoang, D. T., Bannai, D., Nawaz, U., Henson, P., Liu, S., Gage, D. & 21 others, McCarroll, S., Bishop, J. R., Hill, S., Reilly, J. L., Lencer, R., Clementz, B. A., Buckley, P., Glahn, D. C., Meda, S. A., Narayanan, B., Pearlson, G., Keshavan, M. S., Ivleva, E. I., Tamminga, C., Sweeney, J. A., Curtis, D., Badner, J. A., Keedy, S., Rapoport, J., Liu, C. & Gershon, E. S., Dec 1 2019, In : Translational psychiatry. 9, 1, 230.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Once-monthly subcutaneously administered risperidone in the treatment of schizophrenia: Patient considerations

Tchobaniouk, L. V., McAllister, E. E., Bishop, D. L., Carpentier, R. M., Heins, K. R., Haight, R. J. & Bishop, J. R., Jan 1 2019, In : Patient Preference and Adherence. 13, p. 2233-2241 9 p.

Research output: Contribution to journalArticle

Open Access

Orphan drug development: the increasing role of clinical pharmacology

Ahmed, M. A., Okour, M., Brundage, R. & Kartha, R. V., Oct 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 5, p. 395-409 15 p.

Research output: Contribution to journalReview article

3 Scopus citations

Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier

Chernick, D., Ortiz-Valle, S., Jeong, A., Qu, W. & Li, L., Aug 24 2019, In : Neuroscience Letters. 708, 134306.

Research output: Contribution to journalReview article

5 Scopus citations

Pharmacogenetics of treating pediatric anxiety and depression

Ramsey, L. B., Bishop, J. R. & Strawn, J. R., Aug 27 2019, In : Pharmacogenomics. 20, 12, p. 867-870 4 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis

ASTRO-CM Study Team, Dec 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 6, p. 565-576 12 p.

Research output: Contribution to journalArticle

Pharmacy education needs to address diagnostic safety

Graber, M. L., Grice, G. R., Ling, L. J., Conway, J. M. & Olson, A., Jan 1 2019, In : American journal of pharmaceutical education. 83, 6, p. 1179-1188 10 p., 7442.

Research output: Contribution to journalArticle

Portal Vein Thrombosis after Total Pancreatectomy and Islet Autotransplant: Prophylaxis and Graft Impact

Robbins, A. J., Skube, M. E., Bellin, M. D., Dunn, T. B., Chapman, S. A., Berry, K. L., Lusczek, E. & Beilman, G. J., Nov 1 2019, In : Pancreas. 48, 10, p. 1329-1333 5 p.

Research output: Contribution to journalArticle

Preclinical evaluation of an unconventional ruthenium-gold-based chemotherapeutic: RANCE-1, in clear cell renal cell carcinoma

Elie, B. T., Hubbard, K., Pechenyy, Y., Layek, B., Prabha, S. & Contel, M., Jan 1 2019, In : Cancer medicine. 8, 9, p. 4304-4314 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Randomized trial of three anticonvulsant medications for status epilepticus

NETT and PECARN Investigators, Nov 28 2019, In : New England Journal of Medicine. 381, 22, p. 2103-2113 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Reiki for Pain During Hemodialysis: A Feasibility and Instrument Evaluation Study

Zins, S., Hooke, M. C. & Gross, C. R., Jun 1 2019, In : Journal of Holistic Nursing. 37, 2, p. 148-162 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Review of Real-World Implementation Data on Emtricitabine-Tenofovir Disoproxil Fumarate as HIV Pre-exposure Prophylaxis in the United States

Adams, J. L., Shelley, K. & Nicol, M. R., Apr 2019, In : Pharmacotherapy. 39, 4, p. 486-500 15 p.

Research output: Contribution to journalReview article

3 Scopus citations

Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

Grant, M. K. O., Seelig, D. M., Sharkey, L. C., Choi, W. S. V., Abdelgawad, I. Y. & Zordoky, B. N., Feb 2019, In : PloS one. 14, 2, e0212486.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
4 Scopus citations

Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups

the DeKAF Genomics and GEN03 Investigators, Oct 1 2019, In : American Journal of Transplantation. 19, 10, p. 2795-2804 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol

For the EpiBioS4Rx Study Group, Mar 2019, In : Neurobiology of Disease. 123, p. 110-114 5 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, Aug 2019, In : American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

The nonconservative CD177 single-nucleotide polymorphism c.1291G>A is a genetic determinant for human neutrophil antigen-2 atypical/low expression and deficiency

Wu, J., Li, Y., Schuller, R. M., Li, L., Litmeyer, A. S., Bein, G., Sachs, U. J. & Bayat, B., May 2019, In : Transfusion. 59, 5, p. 1836-1842 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial

Sathe, A. G., Tillman, H., Coles, L. D., Elm, J. J., Silbergleit, R., Chamberlain, J., Kapur, J., Cock, H. R., Fountain, N. B., Shinnar, S., Lowenstein, D. H., Conwit, R. A., Bleck, T. P. & Cloyd, J. C., Jan 1 2019, In : Academic Emergency Medicine. 26, 8, p. 940-943 4 p.

Research output: Contribution to journalLetter

3 Scopus citations

Use of herbal medicine by pregnant women: What physicians need to know

Illamola, S. M., Amaeze, O. U., Krepkova, L. V., Birnbaum, A. K., Karanam, A., Job, K. M., Bortnikova, V. V., Sherwin, C. M. T. & Enioutina, E. Y., Jan 1 2019, In : Frontiers in Pharmacology. 10, 1483.

Research output: Contribution to journalArticle

Open Access