Experimental and Clinical Pharmacology

Research Output

Open Access
4 Scopus citations
31 Scopus citations

2005 Human Genome Variation Society Scientific Meeting

Oetting, W. S., Mar 1 2006, In : Human mutation. 27, 3, p. 286-289 4 p.

Research output: Contribution to journalArticle

3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

Aboutabl, M. E., Zordoky, B. N. M. & El-Kadi, A. O. S., Dec 1 2009, In : British Journal of Pharmacology. 158, 7, p. 1808-1819 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

A 16-month community-based intervention to increase aspirin use for primary prevention of cardiovascular disease

Oldenburg, N. C., Duval, S., Luepker, R. V., Finnegan, J. R., LaMarre, H., Peterson, K. A., Zantek, N. D., Jacobs, G., Straka, R. J., Miller, K. H. & Hirsch, A. T., May 2014, In : Preventing Chronic Disease. 11, 5, 130378.

Research output: Contribution to journalArticle

8 Scopus citations

ABCA1 polymorphisms and Alzheimer's disease

Wavrant-De Vrièze, F., Compton, D., Womick, M., Arepalli, S., Adighibe, O., Li, L., Pérez-Tur, J. & Hardy, J., Apr 12 2007, In : Neuroscience Letters. 416, 2, p. 180-183 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique

Browne, T. R., Szabo, G. K., Leppik, I. E., Josephs, E., Paz, J., Baltes, E. & Jensen, C. M., Jan 1 2000, In : Journal of Clinical Pharmacology. 40, 6, p. 590-595 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Absorption characteristics of a new valproate formulation: divalproex sodium-coated particles in capsules (Depakote® Sprinkle)

Carrigan, P. J., Brinker, D. R., Cavanaugh, J. H., Lamm, J. E. & Cloyd, J. C., Jan 1 1990, In : Journal of Clinical Pharmacology. 30, 8, p. 743-747 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy

Hicks, J. K., Bishop, J. R., Gammal, R. S., Sangkuhl, K., Bousman, C. A., Leeder, J. S., Llerena, A., Mueller, D. J., Ramsey, L. B., Scott, S. A., Skaar, T. C., Caudle, K. E., Klein, T. E. & Gaedigk, A., Jan 1 2020, In : Clinical pharmacology and therapeutics. 107, 1, p. 50-52 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

A call for mutations

Cotton, R. G. H., Auerbach, A. D. & Oetting, W. S., May 1 2005, In : Genetics in Medicine. 7, 5, 1 p.

Research output: Contribution to journalLetter

5 Scopus citations
14 Scopus citations

A case-control study provides evidence of association for a common SNP rs974819 in PDGFD to coronary heart disease and suggests a sex-dependent effect

Zhou, J., Huang, Y., Huang, R. S., Wang, F., Xu, L., Le, Y., Yang, X., Xu, W., Huang, X., Lian, J. & Duan, S., Oct 1 2012, In : Thrombosis Research. 130, 4, p. 602-606 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Accumulation of amyloid-β protein in exocrine glands of transgenic mice overexpressing a carboxyl terminal portion of amyloid protein precursor

Fukuchi, K. I., Li, L., Hart, M. & Lindsey, J. R., Jan 1 2000, In : International Journal of Experimental Pathology. 81, 4, p. 231-239 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Achieving cholesterol target in a managed care organization (ACTION) trial

Straka, R. J., Taheri, R., Cooper, S. L. & Smith, J. C., Mar 1 2005, In : Pharmacotherapy. 25, 3, p. 360-371 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Acid ingestion neutralizing agents

Sioris, L. J., Peterson, C. D. & Krenzelok, E. P., Mar 1979, In : Journal of the American College of Emergency Physicians. 8, 3, 1 p.

Research output: Contribution to journalLetter

2 Scopus citations

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptorĝ€"negative breast cancer

Haiman, C. A., Chen, G. K., Vachon, C. M., Canzian, F., Dunning, A., Millikan, R. C., Wang, X., Ademuyiwa, F., Ahmed, S., Ambrosone, C. B., Baglietto, L., Balleine, R., Bandera, E. V., Beckmann, M. W., Berg, C. D., Bernstein, L., Blomqvist, C., Blot, W. J., Brauch, H., Buring, J. E. & 110 others, Carey, L. A., Carpenter, J. E., Chang-Claude, J., Chanock, S. J., Chasman, D. I., Clarke, C. L., Cox, A., Cross, S. S., Deming, S. L., Diasio, R. B., Dimopoulos, A. M., Driver, W. R., Dünnebier, T., Durcan, L., Eccles, D., Edlund, C. K., Ekici, A. B., Fasching, P. A., Feigelson, H. S., Flesch-Janys, D., Fostira, F., Försti, A., Fountzilas, G., Gerty, S. M., Giles, G. G., Godwin, A. K., Goodfellow, P., Graham, N., Greco, D., Hamann, U., Hankinson, S. E., Hartmann, A., Hein, R., Heinz, J., Holbrook, A., Hoover, R. N., Hu, J. J., Hunter, D. J., Ingles, S. A., Irwanto, A., Ivanovich, J., John, E. M., Johnson, N., Jukkola-Vuorinen, A., Kaaks, R., Ko, Y. D., Kolonel, L. N., Konstantopoulou, I., Kosma, V. M., Kulkarni, S., Lambrechts, D., Lee, A. M., Marchand, L. L., Lesnick, T., Liu, J., Lindstrom, S., Mannermaa, A., Margolin, S., Martin, N. G., Miron, P., Montgomery, G. W., Nevanlinna, H., Nickels, S., Nyante, S., Olswold, C., Palmer, J., Pathak, H., Pectasides, D., Perou, C. M., Peto, J., Pharoah, P. D. P., Pooler, L. C., Press, M. F., Pylkäs, K., Rebbeck, T. R., Rodriguez-Gil, J. L., Rosenberg, L., Ross, E., Rüdiger, T., Silva, I. D. S., Sawyer, E., Schmidt, M. K., Schulz-Wendtland, R., Schumacher, F., Severi, G., Sheng, X., Signorello, L. B., Sinn, H. P., Stevens, K. N., Southey, M. C., Tapper, W. J., Tomlinson, I., Hogervorst, F. B. L., Wauters, E., Weaver, J., Wildiers, H., Winqvist, R., Berg, D. V. D., Wan, P., Xia, L. Y., Yannoukakos, D., Zheng, W., Ziegler, R. G., Siddiq, A., Slager, S. L., Stram, D. O., Easton, D., Kraft, P., Henderson, B. E. & Couch, F. J., Dec 1 2011, In : Nature Genetics. 43, 12, p. 1210-1214 5 p.

Research output: Contribution to journalArticle

216 Scopus citations

A comparative assessment of vancomycin-associated nephrotoxicity in the young versus the elderly hospitalized patient

Vance-bryan, K., Rotschafer, J. C., Gilliland, S. S., Rodvold, K. A., Fitzgerald, C. M. & Guay, D. R. P., Apr 1 1994, In : Journal of Antimicrobial Chemotherapy. 33, 4, p. 811-821 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

A comparison of rectal diazepam gel and placebo for acute repetitive seizures

Dreifuss, F. E., Rosman, N. P., Cloyd, J. C., Pellock, J. M., Kuzniecky, R. I., Lo, W. D., Matsuo, F., Sharp, G. B., Conry, J. A., Bergen, D. C. & Bell, W. E., Jun 25 1998, In : New England Journal of Medicine. 338, 26 I, p. 1869-1875 7 p.

Research output: Contribution to journalArticle

188 Scopus citations

A comparison of response rate, data quality, and cost in the collection of data on sexual history and personal behaviors: Mail survey approaches and in-person interview

Rolnick, S. J., Gross, C. R., Garrard, J. & Gibson, R. W., May 1989, In : American journal of epidemiology. 129, 5, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density

Rudolph, A., Fasching, P. A., Behrens, S., Eilber, U., Bolla, M. K., Wang, Q., Thompson, D., Czene, K., Brand, J. S., Li, J., Scott, C., Pankratz, V. S., Brandt, K., Hallberg, E., Olson, J. E., Lee, A., Beckmann, M. W., Ekici, A. B., Haeberle, L., Maskarinec, G. & 20 others, Le Marchand, L., Schumacher, F., Milne, R. L., Knight, J. A., Apicella, C., Southey, M. C., Kapuscinski, M. K., Hopper, J. L., Andrulis, I. L., Giles, G. G., Haiman, C. A., Khaw, K. T., Luben, R., Hall, P., Pharoah, P. D. P., Couch, F. J., Easton, D. F., dos-Santos-Silva, I., Vachon, C. & Chang-Claude, J., Aug 16 2015, In : Breast Cancer Research. 17, 1, 110.

Research output: Contribution to journalArticle

8 Scopus citations

A computerized technique to assess language use patterns in patients with frontotemporal dementia

Pakhomov, S. V. S., Smith, G. E., Marino, S., Birnbaum, A., Graff-Radford, N., Caselli, R., Boeve, B. & Knopman, D. S., Mar 1 2010, In : Journal of Neurolinguistics. 23, 2, p. 127-144 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

A controlled study of progabide in partial seizures: Methodology and results

Leppik, I. E., Dreifuss, F. E., Porter, R., Bowman, T., Santilli, N., Jacobs, M., Crosby, C., Cloyd, J., Stackman, J., Graves, N., Sutula, T., Welty, T., Vickery, J., Brundage, R., Gates, J., Gumnit, R. J. & Gutierrez, A., Jun 1987, In : Neurology. 37, 6, p. 963-968 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

ACoP: The tools, carpenters, and architects building the discipline of pharmacometrics

Brundage, R. C., Pfister, M., D'Argenio, D. Z., Gastonguay, M. R., Miller, R. & Tannenbaum, S. J., Sep 1 2010, In : Journal of Clinical Pharmacology. 50, 9, p. 7S-8S

Research output: Contribution to journalShort survey

Activation of muscarinic acetylcholine receptors via their allosteric binding sites

Jakubík, J., Bačáková, L., Lisá, V., El-Fakahany, E. E. & Tuček, S., Aug 6 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 16, p. 8705-8709 5 p.

Research output: Contribution to journalArticle

96 Scopus citations

Activation of neuronal nitric oxide synthase by m2 muscarinic receptors associated with a small increase in intracellular calcium

Wang, S. Z., Lee, S. Y., Zhu, S. Z., Wotta, D. R., Parsons, A. M. & El-Fakahany, E. E., Jan 1 1997, In : Pharmacology. 55, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Activity of fosfomycin and comparison of several susceptibility testing methods against contemporary urine isolates

Hirsch, E. B., Raux, B. R., Zucchi, P. C., Kim, Y., McCoy, C., Kirby, J. E., Wright, S. B. & Eliopoulos, G. M., Dec 1 2015, In : International Journal of Antimicrobial Agents. 46, 6, p. 642-647 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline

Chen, A., Smith, K. P., Whitfield, B. A., Zucchi, P. C., Lasco, T. M., Bias, T. E., Kirby, J. E. & Hirsch, E. B., Aug 2017, In : Diagnostic Microbiology and Infectious Disease. 88, 4, p. 365-367 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart

Anwar-Mohamed, A., El-Sherbeni, A. A., Kim, S. H., Althurwi, H. N., Zordoky, B. N. M. & El-Kadi, A. O. S., Dec 1 2012, In : Xenobiotica. 42, 12, p. 1235-1247 13 p.

Research output: Contribution to journalArticle

20 Scopus citations

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

Anwar-Mohamed, A., El-Sherbeni, A., Kim, S. H., Elshenawy, O. H., Althurwi, H. N., Zordoky, B. N. M. & El-Kadi, A. O. S., Aug 1 2013, In : Xenobiotica. 43, 8, p. 719-729 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

Zordoky, B. N. M., Anwar-Mohamed, A., Aboutabl, M. E. & El-Kadi, A. O. S., Jan 1 2010, In : Toxicology and Applied Pharmacology. 242, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver

Zordoky, B. N. M., Anwar-Mohamed, A., Aboutabl, M. E. & El-Kadi, A. O. S., Aug 1 2011, In : Drug Metabolism and Disposition. 39, 8, p. 1440-1450 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Acute lorazepam effects on neurocognitive performance

Loring, D. W., Marino, S. E., Parfitt, D., Finney, G. R. & Meador, K. J., Nov 1 2012, In : Epilepsy and Behavior. 25, 3, p. 329-333 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Acute Phenytoin and Primidone Intoxication A Pharmacokinetic Analysis

MATZKE, GARY. R., CLOYD, JAMES. C. & SAWCHUK, RONALD. J., Jan 1 1981, In : The Journal of Clinical Pharmacology. 21, 2-3, p. 92-99 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Acute renal failure and intravenous immune globulin: Occurs with sucrose-stabilized, but not with D-sorbitol-stabilized, formulation

Chapman, S. A., Gilkerson, K. L., Davin, T. D. & Pritzker, M. R., Dec 1 2004, In : Annals of Pharmacotherapy. 38, 12, p. 2059-2067 9 p.

Research output: Contribution to journalReview article

47 Scopus citations

ADAM17_i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study

Junyent, M., Parnell, L. D., Lai, C. Q., Arnett, D. K., Tsai, M. Y., Kabagambe, E. K., Straka, R. J., Province, M., An, P., Smith, C. E., Lee, Y. C., Borecki, I. & Ordovás, J. M., Dec 1 2010, In : Nutrition, Metabolism and Cardiovascular Diseases. 20, 10, p. 698-705 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

ADAM17 activity during human neutrophil activation and apoptosis

Walcheck, B., Herrera, A. H., St. Hill, C., Mattila, P. E., Whitney, A. R. & DeLeo, F. R., Apr 1 2006, In : European Journal of Immunology. 36, 4, p. 968-976 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

ADAM-17-independent shedding of L-selectin

Walcheck, B., Alexander, S. R., St Hill, C. A. & Matala, E., Sep 1 2003, In : Journal of Leukocyte Biology. 74, 3, p. 389-394 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Addressing the issue of channeling bias in observational studies with propensity scores analysis

Lobo, F. S., Wagner, S., Gross, C. R. & Schommer, J. C., Mar 1 2006, In : Research in Social and Administrative Pharmacy. 2, 1, p. 143-151 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Adenosine Triphosphate Quantification Correlates Poorly with Microbial Contamination of Duodenoscopes

Olafsdottir, L. B., Wright, S. B., Smithey, A., Heroux, R., Hirsch, E. B., Chen, A., Lane, B., Sawhney, M. S. & Snyder, G. M., Jun 1 2017, In : Infection Control and Hospital Epidemiology. 38, 6, p. 678-684 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
Open Access
7 Scopus citations

A dimension reduction approach for modeling multi-locus interaction in case-control studies

Basu, S., Pan, W. & Oetting, W. S., Sep 1 2011, In : Human heredity. 71, 4, p. 234-245 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

A dinucleotide deletion (-δGA115) in the tyrosinase gene responsible for type I-A (tyrosinase negative) oculocutaneous albinism in a Pakistani individual

S.oetting, W., P.fryer, J. & A.king, R., Jul 1 1993, In : Human molecular genetics. 2, 7, p. 1047-1048 2 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

ADIPOQ polymorphisms, monounsaturated fatty acids, and obesity risk: The GOLDN study

Warodomwichit, D., Shen, J., Arnett, D. K., Tsai, M. Y., Kabagambe, E. K., Peacock, J. M., Hixson, J. E., Straka, R. J., Province, M. A., An, P., Lai, C. Q., Parnell, L. D., Borecki, I. B. & Ordovas, J. M., Mar 2009, In : Obesity. 17, 3, p. 510-517 8 p.

Research output: Contribution to journalArticle

62 Scopus citations
22 Scopus citations

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

ASTRO-CM Team, Aug 2019, In : The Lancet Infectious Diseases. 19, 8, p. 843-851 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

A double-blind, placebo-controlled study of remacemide hydrochloride in patients with refractory epilepsy following pre-surgical assessment

Devinsky, O., Vazquez, B., Faught, E., Leppik, I. E., Pellock, J. M., Schachter, S., Alderfer, V. & Holdich, T. A. H., Sep 2002, In : Seizure. 11, 6, p. 371-376 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

A DPYD variant (Y186C) in individuals of african ancestry is associated with reduced DPD enzyme activity

Offer, S. M., Lee, A. M., Mattison, L. K., Fossum, C., Wegner, N. J. & Diasio, R. B., Jul 1 2013, In : Clinical pharmacology and therapeutics. 94, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

A DPYD variant (y186c) specific to individuals of african descent in a patient with life-threatening 5-fu toxic effects: Potential for an individualized medicine approach

Saif, M. W., Lee, A. M., Offer, S. M., McConnell, K., Relias, V. & Diasio, R. B., Jan 2014, In : Mayo Clinic Proceedings. 89, 1, p. 131-136 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Advances in pharmacotherapy: recent developments in the treatment of epilepsy

Graves, N. M. & Leppik, I. E., Aug 1993, In : Journal of Clinical Pharmacy and Therapeutics. 18, 4, p. 227-242 16 p.

Research output: Contribution to journalReview article

15 Scopus citations

Adverse events associated with the use of oral cephalosporins/cephems

Mitropoulos, I. F., Rotschafer, J. C. & Rodvold, K. A., Mar 1 2007, In : Diagnostic Microbiology and Infectious Disease. 57, 3 SUPPL., p. S67-S76

Research output: Contribution to journalArticle

20 Scopus citations