Experimental and Clinical Pharmacology

Research Output

1965

EXPERIMENTAL USE OF A SINGLE MECHANICAL VENTRICLE TO REPLACE THE DOG'S

PIERCE, W. S., MORRIS, L., GARDINER, B. N., BURNEY, R. G., LEPPIK, I., MALMUD, L. & DANIELSON, G. K., Dec 1 1965, In : Transactions - American Society for Artificial Internal Organs. 11, p. 271-276 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Total heart replacement by a single intrathoracic blood pump

Pierce, W. S., Gardiner, B. N., Morris, L., Burney, R. G., Leppik, I. E. & Danielson, G. K., Sep 1965, In : Journal of Surgical Research. 5, 9, p. 387-394 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
1971

Studies on the biosynthesis of the mitomycin antibiotics by Streptomyces verticillatus

Hornemann, U. & Cloyd, J. C., Dec 1 1971, In : Journal of the Chemical Society D: Chemical Communications. 7, p. 301-302 2 p.

Research output: Contribution to journalArticle

24 Scopus citations
1975

Anticonvulsant activity of phenytoin in combination with phenobarbital

Leppik, I. E. & Sherwin, A. L., Jan 1 1975, In : Clinical Research. 23, 5, p. 642A

Research output: Contribution to journalArticle

1976

Anticonvulsant activity of phenobarbital and phenytoin in combination

Leppik, I. E. & Sherwin, A. L., Jan 1 1976, In : Pharmacologist. 18, 2

Research output: Contribution to journalArticle

Correlation between red cell and free plasma phenytoin levels in renal disease

Sherwin, A. L., Harvey, C. D., Leppik, I. E. & Gonda, A., Sep 1976, In : Neurology. 26, 9, p. 874-878 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Diplopia and involuntary eye closure in spontaneous cerebellar hemorrhage

Messert, B., Leppik, I. E. & Sato, S., Jan 1 1976, In : Stroke. 7, 3, p. 305-307 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

FIFTH INTERNATIONAL CONGRESS OF HUMAN GENETICS

Leppik, I. E., Andermann, E. & Andermann, F., 1976, EXCERPTA MED.,AMSTERDAM,I.C.S.. Vol. No.397.

Research output: Chapter in Book/Report/Conference proceedingChapter

The Effectiveness of Drug Education Programs: A Critical Review

Berberian, R. M., Gross, C. R., Lovejoy, J. & Paparella, S., Nov 1976, In : Health Education & Behavior. 4, 4, p. 377-398 22 p.

Research output: Contribution to journalReview article

49 Scopus citations
1977

Anticonvulsant activity of phenobarbital and phenytoin in combination

Leppik, I. E. & Sherwin, A. L., Dec 1 1977, In : Journal of Pharmacology and Experimental Therapeutics. 200, 3, p. 570-575 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Diatrizoate in computed cranial tomography: A quantitative study

Lepplk, I. E., Thompson, C. J., Ethier, R. & Sherw1n, A. L., Jan 1 1977, In : Investigative Radiology. 12, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
4 Scopus citations

Hydrochloric acid for the correction of severe metabolic alkalosis: an alternate approach.

Johnson, C. A. & Cloyd, J. C., Mar 1 1977, In : Journal of the Kentucky Medical Association. 75, 3, p. 121-123 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molar solutions and molar concentrations.

Cloyd, J., 1977, In : British Medical Journal. 1, 6061, p. 643 1 p.

Research output: Contribution to journalLetter

Salivary levels of anticonvulsants: A practical approach to drug monitoring

McAuliffe, J. J., Sherwin, A. L., Leppik, I. E., Fayle, S. A. & Pippenger, C. E., May 1977, In : Neurology. 27, 5, p. 409-413 5 p.

Research output: Contribution to journalArticle

110 Scopus citations
1978

Amikacin pharmacokinetics: effect of age on elimination

Rotschafer, J. C., Zaske, D. E. & Cipolle, R. J., Jan 1 1978, In : Clinical Research. 26, 3, p. 594A

Research output: Contribution to journalArticle

Clonazepam in the treatment of epilepsy

Matthews, S. J., Pepin, S. M. & Leppik, I. E., Jan 1 1978, In : Minnesota medicine. 61, 7, p. 439-442 4 p.

Research output: Contribution to journalArticle

COEFFICIENT OF VARIATION AS MEASURE OF COMPLIANCE

Leppik, I. E., Cloyd, J. C. & Sawchuk, R. J., Oct 14 1978, In : The Lancet. 312, 8094, 1 p.

Research output: Contribution to journalLetter

5 Scopus citations

Concentration-time profile of phenytoin after admixture with small volumes of intravenous fluids

Cloyd, J. C., Bosch, D. E. & Sawchuk, R. J., Jan 1 1978, In : American Journal of Hospital Pharmacy. 35, 1, p. 45-48 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Intravenous phenytoin: Clinical and pharmacokinetic aspects

Cranford, R. E., Leppik, I. E., Patrick, B., Anderson, C. B. & Kostick, B., 1978, In : Neurology. 28, 9 I, p. 874-880 7 p.

Research output: Contribution to journalArticle

126 Scopus citations

Pharm. D. for all. Who will provide the necessary resources?

Cipolle, R. J., Cloyd, J. C., McCoy, H. G., Pepin, S. M., Rotschafer, J. C. & Zaske, D. E., Jan 1 1978, In : Unknown Journal. 12, 7, p. 424-425 2 p.

Research output: Contribution to journalEditorial

Phencyclidine intoxication: A literature review

Sioris, L. J. & Krenzelok, E. P., Dec 1 1978, In : American Journal of Hospital Pharmacy. 35, 11, p. 1362-1367 6 p.

Research output: Contribution to journalReview article

34 Scopus citations

Progressive Sensory Loss One Year After Bullet Injury of Spinal Cord

Nino, H. E., Leppik, I. E., Lai, C. W. & Martin, S., Sep 8 1978, In : JAMA: The Journal of the American Medical Association. 240, 11, p. 1173-1174 2 p.

Research output: Contribution to journalArticle

11 Scopus citations
1979

Acid ingestion neutralizing agents

Sioris, L. J., Peterson, C. D. & Krenzelok, E. P., Mar 1979, In : Journal of the American College of Emergency Physicians. 8, 3, 1 p.

Research output: Contribution to journalLetter

2 Scopus citations

Comparative study of cefaclor and amoxicillin in treatment of urinary tract infection

Rotschafer, J., Crossley, K., Zaske, D. & Viste, R., Sep 1979, In : Urology. 14, 3, p. 233-236 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Compliance and variability of plasma phenytoin levels in epileptic patients

Leppik, I. E., Cloyd, J. C., Sawchuk, R. J. & Pepin, S. M., Jan 1 1979, In : Therapeutic drug monitoring. 1, 4, p. 475-483 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Effect of influenza vaccination on plasma phenytoin concentrations

Sawchuk, R. J., Rector, T. S., Fordice, J. J. & Leppik, I. E., Jan 1 1979, In : Therapeutic drug monitoring. 1, 2, p. 285-288 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Increased Clearance of Phenytoin during Infectious Mononucleosis

Leppik, I. E., Ramani, V., Sawchuk, R. J. & Gumnit, R. J., Mar 1 1979, In : New England Journal of Medicine. 300, 9, p. 481-482 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Intravenous administration of phenytoin

Cranford, R. E. & Leppik, I. E., May 1979, In : Neurology. 29, 5, 1 p.

Research output: Contribution to journalLetter

Intravenous Phenytoin and Phenobarbital: Anticonvulsant Action, Brain Content, and Plasma Binding in Rat

Leppik, I. E. & Sherwin, A. L., Jun 1979, In : Epilepsia. 20, 3, p. 201-207 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Intravenous phenytoin in acute treatment of seizures

Cranford, R. E., Leppik, I. E., Patrick, B., Anderson, C. B. & Kostick, B., Nov 1979, In : Neurology. 29, 11, p. 1474-1479 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Pharmacokinetic Properties of Thiopental in Two Patients Treated for Uncontrollable Seizures

Cloyd, J. C., Wright, B. D. & Perrier, D., Jun 1979, In : Epilepsia. 20, 3, p. 313-318 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

PILOT DATA BANK NETWORKS FOR NEUROLOGICAL DISORDERS.

Kunitz, S. C., Havekost, C. L. & Gross, C. R., Jan 1 1979, p. 793-797. 5 p.

Research output: Contribution to conferencePaper

5 Scopus citations

The pharmacokinetics of valproic acid in children

Kriel, R. L., Cloyd, J. C. & Green, K. H., Jan 1 1979, In : Annals of Neurology. 6, 2, 1 p.

Research output: Contribution to journalArticle

6 Scopus citations
1980

Availability of diazepam from plastic containers

Cloyd, J. C., Vezeau, C. & Miller, K. W., Jan 1 1980, In : American Journal of Hospital Pharmacy. 37, 4, p. 492-496 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Clinical pharmacy. Glutethimide overdose. Clinical and kinetic observations of glutethimide and a metabolite

Rotschafer, J. C., Foley, C. & Zaske, D., Jan 1 1980, In : Minnesota medicine. 63, 2, p. 145-147 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Comparison of a radioimmunoassay and a microbiological assay for measurement of serum vancomycin concentrations

Crossley, K. B., Rotschafer, J. C., Chern, M. M., Mead, K. E. & Zaske, D. E., Jan 1 1980, In : Antimicrobial agents and chemotherapy. 17, 4, p. 654-657 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

NATIONAL TRAUMATIC COMA DATA BANK.

Kunitz, S. C., Gross, C. R., Nichols, B. & Edelstein, S., Jan 1 1980, p. 1333-1339. 7 p.

Research output: Contribution to conferencePaper

2 Scopus citations

Neurologic prognosis after cardiopulmonary arrest: II. level of consciousness

Synder, B. D., Loewenson, R. B., Gumnit, R. J., Hauser, W. A., Leppik, I. E. & Ramirez-Lassepas, M., Jan 1980, In : Neurology. 30, 1, p. 52-58 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Neurologic prognosis after cardiopulmonary arrest: III. Seizure activity

Snyder, B. D., Hauser, W. A., Loewenson, R. B., Leppik, I. E., Ramirez-Lassepas, M. & Gumnit, R. J., Dec 1980, In : Neurology. 30, 12, p. 1292-1297 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Phenytoin and Formation of T Lymphocyte Rosettes

Neilan, B. A. & Leppik, I. E., Sep 1980, In : Archives of Neurology. 37, 9, p. 580-581 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Potentiation of Warfarin Anticoagulation by Sulfisoxazole

Sioris, L. J., Weibert, R. T. & Pentel, P. R., Apr 1980, In : Archives of Internal Medicine. 140, 4, p. 546-547 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Reduced seizure control due to spoiled phenytoin capsules

Cloyd, J. C., Gumnit, R. J. & Lesar, T. S., Feb 1980, In : Annals of Neurology. 7, 2, p. 191-193 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Status Epilepticus: The Role of Intravenous Phenytoin

Cloyd, J. C., Gumnit, R. J. & Mclain, L. W., Sep 26 1980, In : JAMA: The Journal of the American Medical Association. 244, 13, p. 1479-1481 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Vancomycin pharmacokinetics

Baker, D., Rotschafer, J. C., Sawchuk, R., Crossley, K. B. & Solem, L. D., Sep 1980, In : The Journal of pediatrics. 97, 3, p. 502-503 2 p.

Research output: Contribution to journalLetter

8 Scopus citations
1981

Acute Phenytoin and Primidone Intoxication A Pharmacokinetic Analysis

MATZKE, GARY. R., CLOYD, JAMES. C. & SAWCHUK, RONALD. J., Jan 1 1981, In : The Journal of Clinical Pharmacology. 21, 2-3, p. 92-99 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Altered phenytoin clearance during febrile illnesses

Leppik, I. A., Fisher, J., Kriel, R. & Sawchuck, R., Jan 1 1981, In : Neurology. 31, 4 II, 1 p.

Research output: Contribution to journalArticle

Bioavailability of reetally administered valproic acid syrup

Cloyd, J. C. & Kriel, R. L., Oct 1981, In : Neurology. 31, 10, p. 1348-1352 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Data banks and clinical trials: From adversaries to complementary tools

Kunitz, S. C., Gross, C. & Heyman, A., May 1981, In : Controlled Clinical Trials. 2, 1, p. 68-69 2 p.

Research output: Contribution to journalArticle

Diluting diazepam injection

Cloyd, J. C., Jan 1 1981, In : American Journal of Hospital Pharmacy. 38, 1, 1 p.

Research output: Contribution to journalArticle