Development of a clinical precision medicine program in ovarian cancer as a paradigm for 21st-century tailored healthcare solution

Organization profile

Organization profile

A key barrier to developing better treatments for ovarian cancer, the deadliest of all female malignancies, is the ability to stratify the disease into clinically meaningful subtypes. This in part explains why the current therapeutic regimen for treating ovarian cancer has had such a low success rate; we are treating a heterogeneous collection of tumors with a “one size fits all” regimen. Despite significant progress in genomics and disease biology, ovarian cancer has not yet moved into the arena of precision medicine. The aim is to integrate comprehensive genomic platforms into a coherent structure and develop a tool to stratify ovarian cancers into specific biological subtypes. We are proposing to prospectively enroll ovarian cancer patients and stratify them into molecular subtypes to develop a precision medicine program to individualize treatment. This universal clinical precision medicine platform can then be applied to other cancers and disease processes.

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  • Projects

    Grand Challenges Research Awards: Phase 1

    1/1/171/1/19

    Project: Grand Challenges

    Research Output

    • 1 Conference contribution

    Preserving privacy and fairness in peer-to-peer data integration

    Elmeleegy, H., Ouzzani, M., Elmagarmid, A. & Abusalah, A., Jul 23 2010, Proceedings of the 2010 International Conference on Management of Data, SIGMOD '10. p. 759-770 12 p. (Proceedings of the ACM SIGMOD International Conference on Management of Data).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • 5 Scopus citations