Clinical and Translational Science Institute

Finished

A Multicenter, Randomized, Open-label Phase 3 Study of Rucaparib versus Physician'sChoice of Therapy for Patients with Metastatic Castration resistant Prostate Cancer Associated withHomologous Recombination Deficiency

4/1/18 → 7/31/23

Project: Research project

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)

Blazar, B. R., AbuSalah, A. M., Adam, T. J., Aliferis, MD, PhD, C., Allen, J., Beckman, K. B., Billings, J. L., Bloomfield, H. E., Bornsztein, B., Brearley, A. M., Call, K. T., Chi, C., Clancy, T. R., Connett, J. E., Daniels, B. S., Eder, M., El-Fakahany, E. E., Fischer, G., Fulkerson, J., Garwood, M., Georgopoulos, A. P., Guan, W., Henderson, J. N., Hodges, J. S., Ingbar, D. H., Jones-Webb, R. J., Jordan, C., Karypis, G., Knights, D., Kumar, V., LeBien, T. W., Lim, K. O., Ma, S., Melton-Meaux, G. B., Myers, C. L., Neuhauser, C., Oakes, M., Okuyemi, K., Pakhomov, S. V., Panoskaltsis-Mortari, A., Pieczkiewicz, D. S., Raymond, N. C., Riggs, S., Rudser, K., Ruggles, S., Schacker, T. W., Schleiss, M. R., Shekhar, S., Shen, S., Simon, G. J., Ugurbil, K., Vock, D. M., Volkov, B. B., Wang, J., Warren, R., Weber-Main, A. M., Weisdorf, D. J., Wolf, S. M., Zellmer-Bruhn, M. E. & Zhang, R.

NIH NAT'L CTR FOR ADVANCING TRAN SCIENCE

3/30/18 → 11/17/23

Project: Research project

A Phase 3 Open-label, Multicenter Study to Evaluate the

Pritzker, M. R.

LIQUIDIA TECHNOLOGIES, INC

2/8/18 → 3/28/22

Project: Research project

The HeartFlow REFINE Registry: RetrospectivE study of FF

Nijjar, P. S.

HEARTFLOW, INC

2/1/18 → 1/30/21

Project: Research project

PROVIDE-HF: Patient Reported Outcomes inVestigation foll

Alexy, T.

UNIVERSITY OF KANSAS MEDICAL CENTER, NOVARTIS PHARMACEUTICALS CORPORATION

1/12/18 → 12/31/19

Project: Research project

A Multicenter, Randomized, Double-blind, Placebo control

Pritzker, M. R.

IRONWOOD PHARMACEUTICALS, INC

1/1/18 → 1/30/21

Project: Research project

Phase Ib/II Trial of Interleukin-2 and PD-1 Checkpoint I

Ryan, C., Gupta, S. & Rao, A.

UNIVERSITY OF MICHIGAN, PROMETHEUS LABORATORIES, INC.

12/19/17 → 1/4/22

Project: Research project

Phase II Study of Pembrolizumab in Combination with Carboplatin and Paclitaxel for Advanced or Recurrent Endometrial Adenocarcinoma

Teoh, D. G.

BIG TEN CANCER RESEARCH CONSORTIUM

12/1/17 → 11/30/22

Project: Research project

Assessment of Surrogate Sensors for Hypertension (ASSH)

Benditt, D. G.

MEDTRONIC INC

12/1/17 → 7/31/18

Project: Research project

A Phase II Trial of Chemotherapy plus Pembrolizumab in patients with advanced NSCLC previously treatedwith PD-1 or PD-L1 Inhibitor: Big Ten Cancer Research Consortium BTCRC-LUN15-029

Fujioka, N.

BIG TEN CANCER RESEARCH CONSORTIUM, MERCK AND CO INC

12/1/17 → 11/30/22

Project: Research project

Phase 1-2 Study of ADI-PEG 20 plus FOLFOX in Subjects withAdvanced Gastrointestinal Malignancies

Greeno, E. W.

Polaris Pharmaceuticals, Inc.

12/1/17 → 11/30/22

Project: Research project

HM2017-39 Phase III Randomized Study of Crenolanib versus Midostaurin Administered FollowingInduction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 MutatedAcute Myeloid Leukemia

Warlick, E. D.

AROG PHARMACEUTICALS, INC

12/1/17 → 11/30/23

Project: Research project

Clinical Presentation, Treatment, and Outcome

Holtan, S. G.

INCYTE CORPORATION

11/13/17 → 2/28/21

Project: Research project

HM2017-33 : Nivolumab and Oral Cyclophosphamide for Rela

Maakaron, J., He, F. & Weisdorf, D. J.

BRISTOL-MYERS SQUIBB COMPANY

11/1/17 → 4/30/23

Project: Research project

HM2017-41: LONG-TERM FOLLOW-UP STUDY OF SUBJECTS TREATED

Bachanova, V.

UNUM THERAPEUTICS, INC.

11/1/17 → 11/30/22

Project: Research project

A Phase 3, INterVentional, Double-Blind, Placebo-Control

Skubitz, K.

DECIPHERA PHARMACEUTICALS, LLC

11/1/17 → 5/31/21

Project: Research project

A phase 1B/2 study to evaluate safety and anti-tumor act

Ryan, C. & Gupta, S.

PFIZER, INC.

11/1/17 → 11/30/22

Project: Research project

A Phase 2/3 Randomized, Open-Label Study of Toca 511, a

Chen, C. C.

TOCAGEN INC.

11/1/17 → 11/30/20

Project: Research project

Transfemoral Replacement of Aortic Valve with HLT MeriDI

Raveendran, G.

HEART LEAFLET TECHNOLOGIES, INC

11/1/17 → 11/30/22

Project: Research project

INCLISIRAN A PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZE

Duprez, D.

THE MEDICINES COMPANY

11/1/17 → 3/30/18

Project: Research project

Evaluation of the Safety of Poziotinib in Combination With TDM1 in Women with Advanced or MetastaticHER2+ Breast Cancer

Potter, D. A.

SPECTRUM PHARMACEUTICALS, INC

10/17/17 → 7/1/19

Project: Research project

Multicenter, Randomized, Double-blind, Placebo-controlle

Thenappan, T.

UNITED THERAPEUTICS CORPORATION

10/1/17 → 11/14/19

Project: Research project

An Open-label Extension Study of Oral Treprostinil in Su

Thenappan, T.

UNITED THERAPEUTICS CORPORATION

10/1/17 → 11/14/19

Project: Research project

A Two-Stage, Open-Label Followed by Placebo-C

Warlick, E. D.

MEI PHARMA, INC

10/1/17 → 5/31/21

Project: Research project

CITN-05: A Pilot Study of the Immunological Effects of N

Miller, J. S.

FRED HUTCHINSON CANCER CENTER, NIH NATIONAL CANCER INSTITUTE (NCI)

9/21/17 → 8/31/18

Project: Research project

CITN-06:A Phase 1 Study of the Clinical and Immunologic

Holtan, S. G.

FRED HUTCHINSON CANCER CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)

9/21/17 → 8/31/19

Project: Research project

CHARACTERIZING THE BURDEN OF CAREGIVERS OF INDIVIDUALS WITH GLIOBLASTOMA MULTIFORME(GBM)

Neil, E. C.

THE UNIVERSITY OF UTAH, BRISTOL-MYERS SQUIBB COMPANY

9/1/17 → 9/30/22

Project: Research project

INvesTigation to OptimizE Hemodynamic Management of Hear

Cogswell, R. J.

ABBOTT LABS GLOBAL PHARM RES & DEV

9/1/17 → 9/30/22

Project: Research project

A Phase II Study of TAK-228 in patients with previously

Ryan, C. & Gupta, S.

DANA-FARBER CANCER INSTITUTE, MILLENNIUM PHARMACEUTICALS, INC.

9/1/17 → 9/30/22

Project: Research project

The Amplatzer Post-infarct Muscular VSD Occluder Humanit

Raveendran, G.

ABBOTT LABORATORIES

9/1/17 → 9/30/22

Project: Research project

A Prospective, Single-Arm, Multicenter Study to Investig

Helmer, G. A.

EDWARDS LIFESCIENCES LLC

8/1/17 → 12/12/19

Project: Research project

Phase I Study of ACTR707, an Autologous T cell Product,

Bachanova, V.

UNUM THERAPEUTICS, INC.

8/1/17 → 8/30/21

Project: Research project

FATE-NK100 as Monotherapy and in Combination with Monocl

Patel, M. R.

FATE THERAPEUTICS, INC.

8/1/17 → 12/31/22

Project: Research project

Intraperitoneal Delivery of Adaptive Natural Killer (NK)

Geller, M. A.

FATE THERAPEUTICS, INC.

7/1/17 → 7/30/22

Project: Research project

A Randomized, Double-Blind, Placebo-Controlled Study of

Duprez, D.

REGENERON PHARMACEUTICALS, INC.

6/1/17 → 5/30/22

Project: Research project

A Randomized, Double-Blind, Placebo-Controlled Study to

Duprez, D.

ESPERION THERAPEUTICS, INC.

4/1/17 → 6/30/23

Project: Research project

Randomized Controlled Pivotal Trial of Autologous Bone M

Raveendran, G. & Missov, E.

BIOCARDIA

3/1/17 → 5/31/20

Project: Research project

A phase 1, open-label dose-escalation study of SEA-CD40 in adult patients with advancedmalignancies

Bachanova, V.

SEAGEN INC

3/1/17 → 2/28/21

Project: Research project

Influenza Vaccine in Effectively Stop Cardio Thoracic Ev

Cogswell, R. J.

BRIGHAM AND WOMEN'S HOSPITAL, NATIONAL INSTITUTES OF HEALTH (NIH)

2/1/17 → 9/30/19

Project: Research project

A randomized, double-blindphase 3 study of vadastuximab

Bejanyan, N.

SEAGEN INC

1/1/17 → 9/1/17

Project: Research project

mRNA-2416-P101

Teoh, D. G. & Gupta, S.

MODERNATX, INC.

1/1/17 → 1/30/23

Project: Research project

An Open Label Phase 2 Study of MLN0128 in Combination wi

Potter, D. A.

MILLENNIUM PHARMACEUTICALS, INC.

1/1/17 → 1/30/23

Project: Research project

GOG-286B A Randomized Phase I/II Study of Paclitaxel/Car

Geller, M. A.

GYNECOLOGIC ONCOLOGY GROUP

1/1/17 → 12/31/20

Project: Research project

A Parallel Phase 2 Study of Glesatinib, Sitravatinib or

Patel, M. R.

MIRATI THERAPEUTICS, INC.

1/1/17 → 6/30/22

Project: Research project

HM2017-02 A randomized, double-blind, placebo-controlled

Bejanyan, N.

SEAGEN INC

1/1/17 → 10/1/17

Project: Research project

Phase I Trial of Intratumoral Administration of Vesicula

Patel, M. R.

VYRIAD

1/1/17 → 1/1/23

Project: Research project

A Randomized, Double-blind, Multicenter, Active-controll

Rittberg, B. R.

JANSSEN RESEARCH & DEVELOPMENT, LLC

12/20/16 → 11/30/20

Project: Research project

A Randomized, Double-blind, Multicenter, Active-controll

Rittberg, B. R.

JANSSEN RESEARCH & DEVELOPMENT, LLC

12/20/16 → 11/30/20

Project: Research project

Phase II Study of Four Concentrations of Intraperitoneal

Mullany, S. A.

U.S. BIOTEST, INC.

12/15/16 → 12/30/21

Project: Research project

Phase II randomized study of pembrolizumab with or witho

Winterhoff, B. J.

TRANSLATIONAL RESEARCH IN ONCOLOGY

12/1/16 → 6/30/22

Project: Research project

Clinical and Translational Science Institute

Projects

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