Research Output

Filter
Article
2019
Open Access
1 Scopus citations

nNOS-PSD95 interactions activate the PKC-ε isoform leading to increased GluN1 phosphorylation and the development of neuropathic mechanical allodynia in mice

Choi, S. R., Han, H. J., Beitz, A. J. & Lee, J. H., Jun 11 2019, In : Neuroscience Letters. 703, p. 156-161 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
1 Scopus citations
2017

Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain

Choi, S. R., Moon, J. Y., Roh, D. H., Yoon, S. Y., Kwon, S. G., Choi, H. S., Kang, S. Y., Han, H. J., Beitz, A. J. & Lee, J. H., Apr 1 2017, In : Journal of Pain. 18, 4, p. 415-427 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

The role of spinal interleukin-1β and astrocyte connexin 43 in the development of mirror-image pain in an inflammatory pain model

Choi, H. S., Roh, D. H., Yoon, S. Y., Kwon, S. G., Choi, S. R., Kang, S. Y., Moon, J. Y., Han, H. J., Kim, H. W., Beitz, A. J. & Lee, J. H., Jan 1 2017, In : Experimental Neurology. 287, p. 1-13 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice

Choi, S. R., Roh, D. H., Yoon, S. Y., Kwon, S. G., Choi, H. S., Han, H. J., Beitz, A. J. & Lee, J. H., Dec 1 2016, In : Neuropharmacology. 111, p. 34-46 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Estimating local biodiversity change: a critique of papers claiming no net loss of local diversitY

Gonzalez, A. H., Cardinale, B. J., Allington, G. R. H., Byrnes, J., Endsley, K. A., Brown, D. G., Hooper, D. U., Isbell, F., Loreau, M. & O'Connor, M. I., 2016, In : Ecology. 97, 8, p. 1949-1960 12 p.

Research output: Contribution to journalArticle

108 Scopus citations

Neuronal NOS activates spinal NADPH oxidase 2 contributing to central sigma-1 receptor-induced pain hypersensitivity in mice

Choi, S. R., Kwon, S. G., Choi, H. S., Han, H. J., Beitz, A. J. & Lee, J. H., Jan 1 2016, In : Biological and Pharmaceutical Bulletin. 39, 12, p. 1922-1931 10 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Overexpression of copper/zinc superoxide dismutase in the median preoptic nucleus improves cardiac function after myocardial infarction in the rat

Collister, J. P., Hartnett, C., Mayerhofer, T., Nahey, D., Stauthammer, C., Krüger, M., Tobias, A., O'Sullivan, M. G., Parker, J., Tian, J., Case, A. J. & Zimmerman, M. C., Oct 1 2016, In : Clinical and Experimental Pharmacology and Physiology. 43, 10, p. 960-966 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Peripheral neurosteroids enhance P2X receptor-induced mechanical allodynia via a sigma-receptor-mediated mechanism

Kwon, S. G., Yoon, S. Y., Roh, D. H., Choi, S. R., Choi, H. S., Moon, J. Y., Kang, S. Y., Beitz, A. J. & Lee, J. H., Mar 1 2016, In : Brain Research Bulletin. 121, p. 227-232 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Repetitive acupuncture point treatment with diluted bee venom relieves mechanical allodynia and restores intraepidermal nerve fiber loss in oxaliplatin-induced neuropathic mice

Yeo, J. H., Yoon, S. Y., Kwon, S. K., Kim, S. J., Lee, J. H., Beitz, A. J. & Roh, D. H., Mar 1 2016, In : Journal of Pain. 17, 3, p. 298-309 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors

Kwon, S. G., Roh, D. H., Yoon, S. Y., Choi, S. R., Choi, H. S., Moon, J. Y., Kang, S. Y., Kim, H. W., Han, H. J., Beitz, A. J., Oh, S. B. & Lee, J. H., Apr 1 2016, In : European Journal of Pain (United Kingdom). 20, 4, p. 594-606 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Colocalization of aromatase in spinal cord astrocytes: Differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor

O'Brien, E. E., Smeester, B. A., Michlitsch, K. S., Lee, J. H. & Beitz, A. J., Aug 1 2015, In : Neuroscience. 301, p. 235-245 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Microglial interleukin-1β in the ipsilateral dorsal horn inhibits the development of mirror-image contralateral mechanical allodynia through astrocyte activation in a rat model of inflammatory pain

Choi, H. S., Roh, D. H., Yoon, S. Y., Moon, J. Y., Choi, S. R., Kwon, S. G., Kang, S. Y., Han, H. J., Kim, H. W., Beitz, A. J., Oh, S. B. & Lee, J. H., Jan 1 2015, In : Pain. 156, 6, p. 1046-1059 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Spinal sigma-1 receptor activation increases the production of d-serine in astrocytes which contributes to the development of mechanical allodynia in a mouse model of neuropathic pain

Moon, J. Y., Choi, S. R., Roh, D. H., Yoon, S. Y., Kwon, S. G., Choi, H. S., Kang, S. Y., Han, H. J., Kim, H. W., Beitz, A. J., Oh, S. B. & Lee, J. H., Oct 1 2015, In : Pharmacological Research. 100, p. 353-364 12 p., 2916.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain

Kwon, S. G., Roh, D. H., Yoon, S. Y., Moon, J. Y., Choi, S. R., Choi, H. S., Kang, S. Y., Han, H. J., Beitz, A. J., Oh, S. B. & Lee, J. H., Jan 9 2014, In : Molecular Pain. 10, 1, 2.

Research output: Contribution to journalArticle

24 Scopus citations

Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expression in carrageenan-induced inflammatory pain rats: Involvement of p38 MAPK phosphorylation in DRGs

Kwon, S. G., Roh, D. H., Yoon, S. Y., Moon, J. Y., Choi, S. R., Choi, H. S., Kang, S. Y., Han, H. J., Beitz, A. J. & Lee, J. H., Apr 1 2014, In : Neuropharmacology. 79, p. 368-379 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Suppression of adrenal gland-derived epinephrine enhances the corticosterone-induced antinociceptive effect in the mouse formalin test

Kang, S. Y., Roh, D. H., Kim, H. W., Han, H. J., Beitz, A. J. & Lee, J. H., May 2014, In : European Journal of Pain (United Kingdom). 18, 5, p. 617-628 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
26 Scopus citations

σ1 receptors activate astrocytes via p38 MAPK phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain

Moon, J. Y., Roh, D. H., Yoon, S. Y., Choi, S. R., Kwon, S. G., Choi, H. S., Kang, S. Y., Han, H. J., Beitz, A. J., Oh, S. B. & Lee, J. H., Dec 2014, In : British Journal of Pharmacology. 171, 24, p. 5881-5897 17 p.

Research output: Contribution to journalArticle

38 Scopus citations
2013
3 Scopus citations
56 Scopus citations

Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats

Moon, J. Y., Roh, D. H., Yoon, S. Y., Kang, S. Y., Choi, S. R., Kwon, S. G., Choi, H. S., Han, H. J., Beitz, A. J. & Lee, J. H., Sep 1 2013, In : Experimental Neurology. 247, p. 383-391 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats

Choi, S. R., Roh, D. H., Yoon, S. Y., Kang, S. Y., Moon, J. Y., Kwon, S. G., Choi, H. S., Han, H. J., Beitz, A. J., Oh, S. B. & Lee, J. H., Oct 4 2013, In : Pharmacological Research. 74, p. 56-67 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

The effect of electroacupuncture on osteosarcoma tumor growth and metastasis: Analysis of different treatment regimens

Smeester, B. A., Al-Gizawiy, M., O'Brien, E. E., Ericson, M. E., Triemstra, J. L. & Beitz, A. J., Nov 18 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 387169.

Research output: Contribution to journalArticle

11 Scopus citations

Transplantation of human umbilical cord blood or amniotic epithelial stem cells alleviates mechanical allodynia after spinal cord injury in rats

Roh, D. H., Seo, M. S., Choi, H. S., Park, S. B., Han, H. J., Beitz, A. J., Kang, K. S. & Lee, J. H., Sep 11 2013, In : Cell transplantation. 22, 9, p. 1577-1590 14 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment

Long, C., Reza Hosseinkhani, M., Wang, Y., Sriramarao, P. & Walcheck, B., Sep 1 2012, In : Journal of Leukocyte Biology. 92, 3, p. 667-672 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors

Brink, T. S., Pacharinsak, C., Khasabov, S. G., Beitz, A. J. & Simone, D. A., Feb 1 2012, In : Journal of neurophysiology. 107, 4, p. 1210-1221 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
10 Scopus citations

Repetitive treatment with diluted bee venom reduces neuropathic pain via potentiation of locus coeruleus noradrenergic neuronal activity and modulation of spinal NR1 phosphorylation in rats

Kang, S. Y., Roh, D. H., Yoon, S. Y., Moon, J. Y., Kim, H. W., Lee, H. J., Beitz, A. J. & Lee, J. H., Feb 1 2012, In : Journal of Pain. 13, 2, p. 155-166 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia

Moon, J. Y., Song, S., Yoon, S. Y., Roh, D. H., Kang, S. Y., Park, J. H., Beitz, A. J. & Lee, J. H., Jan 1 2012, In : Anesthesia and analgesia. 114, 1, p. 215-223 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Acidic pH facilitates peripheral αβmeATP-mediated nociception in rats: Differential roles of P2X, P2Y, ASIC and TRPV1 receptors in ATP-induced mechanical allodynia and thermal hyperalgesia

Seo, H. S., Roh, D. H., Kwon, S. G., Yoon, S. Y., Kang, S. Y., Moon, J. Y., Choi, S. R., Beitz, A. J. & Lee, J. H., Mar 1 2011, In : Neuropharmacology. 60, 4, p. 580-586 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Chemical stimulation of the ST36 acupoint reduces both formalin-induced nociceptive behaviors and spinal astrocyte activation via spinal alpha-2 adrenoceptors

Kang, S. Y., Kim, C. Y., Roh, D. H., Yoon, S. Y., Park, J. H., Lee, H. J., Beitz, A. J. & Lee, J. H., Nov 25 2011, In : Brain Research Bulletin. 86, 5-6, p. 412-421 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Spinal neuronal NOS activation mediates sigma-1 receptor-induced mechanical and thermal hypersensitivity in mice: Involvement of PKC-dependent GluN1 phosphorylation

Roh, D. H., Choi, S. R., Yoon, S. Y., Kang, S. Y., Moon, J. Y., Kwon, S. G., Han, H. J., Beitz, A. J. & Lee, J. H., Aug 1 2011, In : British Journal of Pharmacology. 163, 8, p. 1707-1720 14 p.

Research output: Contribution to journalArticle

54 Scopus citations
2010

Activation of spinal α-2 adrenoceptors, but not μ-opioid receptors, reduces the intrathecal n-methyl-d-aspartate-induced increase in spinal nr1 subunit phosphorylation and nociceptive behaviors in the rat

Roh, D. H., Seo, H. S., Yoon, S. Y., Song, S., Han, H. J., Beitz, A. J. & Lee, J. H., Feb 2010, In : Anesthesia and analgesia. 110, 2, p. 622-629 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis

Wang, Y., Zhang, A. C., Ni, Z., Herrera, A. & Walcheck, B., Apr 15 2010, In : Journal of Immunology. 184, 8, p. 4447-4454 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

An increase in spinal dehydroepiandrosterone sulfate (DHEAS) enhances NMDA-induced pain via phosphorylation of the NR1 subunit in mice: Involvement of the sigma-1 receptor

Yoon, S. Y., Roh, D. H., Seo, H. S., Kang, S. Y., Moon, J. Y., Song, S., Beitz, A. J. & Lee, J. H., Nov 1 2010, In : Neuropharmacology. 59, 6, p. 460-467 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Intrathecal injection of carbenoxolone, a gap junction decoupler, attenuates the induction of below-level neuropathic pain after spinal cord injury in rats

Roh, D. H., Yoon, S. Y., Seo, H. S., Kang, S. Y., Han, H. J., Beitz, A. J. & Lee, J. H., Jul 1 2010, In : Experimental Neurology. 224, 1, p. 123-132 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis

Long, C., Wang, Y., Herrera, A. H., Horiuchi, K. & Walcheck, B., Jun 1 2010, In : Journal of Leukocyte Biology. 87, 6, p. 1097-1101 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Peripheral acid-sensing ion channels and P2X receptors contribute to mechanical allodynia in a rodent thrombus-induced ischemic pain model

Seo, H. S., Roh, D. H., Yoon, S. Y., Kang, S. Y., Moon, J. Y., Kim, H. W., Han, H. J., Chung, J. M., Beitz, A. J. & Lee, J. H., Mar 23 2010, In : Journal of Pain. 11, 8, p. 718-727 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Sigma-1 receptor-induced increase in murine spinal NR1 phosphorylation is mediated by the PKCα and e{open}, but not the PKCζ, isoforms

Roh, D. H., Yoon, S. Y., Seo, H. S., Kang, S. Y., Moon, J. Y., Song, S., Beitz, A. J. & Lee, J. H., Jun 1 2010, In : Neuroscience Letters. 477, 2, p. 95-99 5 p.

Research output: Contribution to journalArticle

28 Scopus citations
2009

Acupoint Stimulation With Diluted Bee Venom (Apipuncture) Potentiates the Analgesic Effect of Intrathecal Clonidine in the Rodent Formalin Test and in a Neuropathic Pain Model

Yoon, S. Y., Roh, D. H., Kwon, Y. B., Kim, H. W., Seo, H. S., Han, H. J., Lee, H. J., Beitz, A. J. & Lee, J. H., Mar 1 2009, In : Journal of Pain. 10, 3, p. 253-263 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Cutaneous lymphocyte-associated antigen (CLA) T cells up-regulate P-selectin ligand expression upon their activation

Ni, Z. & Walcheck, B., Nov 1 2009, In : Clinical Immunology. 133, 2, p. 257-264 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: Involvement of spinal sigma-1 and GABA A receptors

Yoon, S. Y., Roh, D. H., Seo, H. S., Kang, S. Y., Han, H. J., Beitz, A. J. & Lee, J. H., Jun 1 2009, In : British Journal of Pharmacology. 157, 4, p. 666-673 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Regulation of mature ADAM17 by redox agents for L-selectin shedding

Wang, Y., Herrera, A. H., Li, Y., Belani, K. K. & Walcheck, B., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2449-2457 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model

Schiller, K. R., Zillhardt, M. R., Alley, J., Borjesson, D. L., Beitz, A. J. & Mauro, L. J., Feb 3 2009, In : BMC Cancer. 9, 45.

Research output: Contribution to journalArticle

15 Scopus citations
29 Scopus citations
2008

Activation of spinal microglia in a murine model of peripheral inflammation-induced, long-lasting contralateral allodynia

Schreiber, K. L., Beitz, A. J. & Wilcox, G. L., Jul 25 2008, In : Neuroscience Letters. 440, 1, p. 63-67 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice

Kim, H. W., Roh, D. H., Yoon, S. Y., Seo, H. S., Kwon, Y. B., Han, H. J., Kim, K. W., Beitz, A. J. & Lee, J. H., Jul 1 2008, In : British Journal of Pharmacology. 154, 5, p. 1125-1134 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Analysis of nociception, sex and peripheral nerve innervation in the TMEV animal model of multiple sclerosis

Lynch, J. L., Gallus, N. J., Ericson, M. E. & Beitz, A. J., Jun 15 2008, In : Pain. 136, 3, p. 293-304 12 p.

Research output: Contribution to journalArticle

33 Scopus citations