Research Output 1971 2020

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Review article
2019
2 Citations (Scopus)

Use of paramagnetic systems to speed-up NMR data acquisition and for structural and dynamic studies

Kocman, V., Di Mauro, G. M., Veglia, G. & Ramamoorthy, A., Oct 1 2019, In : Solid State Nuclear Magnetic Resonance. 102, p. 36-46 11 p.

Research output: Contribution to journalReview article

data acquisition
Data acquisition
Nuclear magnetic resonance
Membranes
Relaxation time
2018
4 Citations (Scopus)

Actin-myosin interaction: Structure, function and drug discovery

Guhathakurta, P., Prochniewicz, E. & Thomas, D. D., Sep 5 2018, In : International journal of molecular sciences. 19, 9, 2628.

Research output: Contribution to journalReview article

Open Access
myosins
Drug Discovery
Myosins
Actins
drugs
9 Citations (Scopus)

Diiron monooxygenases in natural product biosynthesis

Komor, A. J., Jasniewski, A. J., Que, L. & Lipscomb, J. D., Jul 1 2018, In : Natural Product Reports. 35, 7, p. 646-659 14 p.

Research output: Contribution to journalReview article

Biosynthesis
Mixed Function Oxygenases
Biological Products
Amines
Hydroxylation
14 Citations (Scopus)

Galectins as molecular targets for therapeutic intervention

Dings, R. P. M., Miller, M. C., Griffin, R. J. & Mayo, K. H., Mar 19 2018, In : International journal of molecular sciences. 19, 3, 905.

Research output: Contribution to journalReview article

Open Access
Galectins
cancer
effectors
Epitopes
Biological Phenomena
42 Citations (Scopus)

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies

Chipot, C., Dehez, F., Schnell, J. R., Zitzmann, N., Pebay-Peyroula, E., Catoire, L. J., Miroux, B., Kunji, E. R. S., Veglia, G., Cross, T. A. & Schanda, P., Apr 11 2018, In : Chemical Reviews. 118, 7, p. 3559-3607 49 p.

Research output: Contribution to journalReview article

Open Access
Phosphorylcholine
Detergents
Membrane Proteins
Nuclear magnetic resonance
Biological membranes
5 Citations (Scopus)
Excited states
Membrane Proteins
Nuclear magnetic resonance
Experiments
Sarcoplasmic Reticulum Calcium-Transporting ATPases
2 Citations (Scopus)

Probing protein-protein interactions using asymmetric labeling and carbonyl-carbon selective heteronuclear NMR spectroscopy

Larsen, E. K., Olivieri, C., Walker, C., Manu, V. S., Gao, J., Bernlohr, D. A., Tonelli, M., Markley, J. L. & Veglia, G., Jan 1 2018, In : Molecules. 23, 8, 1937.

Research output: Contribution to journalReview article

Open Access
Biomolecular Nuclear Magnetic Resonance
Labeling
Nuclear magnetic resonance spectroscopy
marking
Magnetic Resonance Spectroscopy
2017
2 Citations (Scopus)

The Ca2+-ATPase pump facilitates bidirectional proton transport across the sarco/endoplasmic reticulum

Espinoza-Fonseca, L. M., Jan 1 2017, In : Molecular BioSystems. 13, 4, p. 633-637 5 p.

Research output: Contribution to journalReview article

Open Access
Calcium-Transporting ATPases
Endoplasmic Reticulum
Protons
Cytosol
Sarcoplasmic Reticulum Calcium-Transporting ATPases
2014
26 Citations (Scopus)
Dioxygenases
Catalytic Domain
3,4-dihydroxyphenylacetate 2,3-dioxygenase
Metals
Electrons
19 Citations (Scopus)

Fluorescence lifetime plate reader: Resolution and precision meet high-throughput

Petersen, K. J., Peterson, K. C., Muretta, J. M., Higgins, S. E., Gillispie, G. D. & Thomas, D. D., Nov 1 2014, In : Review of Scientific Instruments. 85, 11, 113101.

Research output: Contribution to journalReview article

readers
Fluorescence
Throughput
life (durability)
fluorescence
2013
17 Citations (Scopus)

Role of conformational entropy in the activity and regulation of the catalytic subunit of protein kinase A

Veglia, G. & Cembran, A., Nov 1 2013, In : FEBS Journal. 280, 22, p. 5608-5615 8 p.

Research output: Contribution to journalReview article

Cyclic AMP-Dependent Protein Kinase Catalytic Subunits
Entropy
Cyclic AMP-Dependent Protein Kinases
Phosphotransferases
Protein Kinase C
23 Citations (Scopus)
Membrane Proteins
Nuclear magnetic resonance
membranes
solid state
proteins
27 Citations (Scopus)

Solution-processable graphene quantum dots

Zhou, X., Guo, S. & Zhang, J., Aug 26 2013, In : ChemPhysChem. 14, 12, p. 2627-2640 14 p.

Research output: Contribution to journalReview article

Graphite
Semiconductor quantum dots
graphene
quantum dots
Biological systems
2012
10 Citations (Scopus)

Structural dynamics of muscle protein phosphorylation

Colson, B. A., Gruber, S. J. & Thomas, D. D., Aug 29 2012, In : Journal of muscle research and cell motility. 33, 6, p. 419-429 11 p.

Research output: Contribution to journalReview article

Phosphorylation
Muscle Proteins
Structural dynamics
Phosphoproteins
Proteins
2010
27 Citations (Scopus)

Unlocking the eukaryotic membrane protein structural proteome

Lee, J. K. & Stroud, R. M., Aug 1 2010, In : Current Opinion in Structural Biology. 20, 4, p. 464-470 7 p.

Research output: Contribution to journalReview article

Proteome
Membrane Proteins
Bacterial Proteins
Eukaryotic Cells
Crystallization
2009
39 Citations (Scopus)

Site-directed spectroscopic probes of actomyosin structural dynamics

Thomas, D. D., Kast, D. & Korman, V. L., Nov 26 2009, In : Annual Review of Biophysics. 38, 1, p. 347-369 23 p.

Research output: Contribution to journalReview article

Actomyosin
Structural dynamics
Myosins
Actins
Muscle
2008
112 Citations (Scopus)

Mechanism of extradiol aromatic ring-cleaving dioxygenases

Lipscomb, J. D., Dec 1 2008, In : Current Opinion in Structural Biology. 18, 6, p. 644-649 6 p.

Research output: Contribution to journalReview article

Dioxygenases
Metals
Oxygen
Biomimetics
Catalytic Domain
2 Citations (Scopus)

Novel therapeutic agents against endotoxemia and septic shock

Mayo, K. H., Jan 1 2008, In : Drugs of the Future. 33, 1, p. 65-73 9 p.

Research output: Contribution to journalReview article

Endotoxemia
Septic Shock
Lipopolysaccharides
Cytokines
Bacterial Infections
2007
14 Citations (Scopus)

Identification of novel drug targets for angiostatic cancer therapy; it takes two to tango

Thijssen, V. L. J. L., van Beijnum, J. R., Mayo, K. H. & Griffioen, A. W., Dec 1 2007, In : Current Pharmaceutical Design. 13, 35, p. 3576-3583 8 p.

Research output: Contribution to journalReview article

Endothelial Cells
Pharmaceutical Preparations
Neoplasms
Angiogenesis Inhibitors
Endothelium
71 Citations (Scopus)

Substrate activation for O2 reactions by oxidized metal centers in biology

Pau, M. Y. M., Lipscomb, J. D. & Solomon, E. I., Nov 20 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 47, p. 18355-18362 8 p.

Research output: Contribution to journalReview article

Metals
Enzymes
Dioxygenases
Iron
Electrons
2006
40 Citations (Scopus)

Biological chemistry of organotin compounds: Interactions and dealkylation by dithiols

Buck-Koehntop, B. A., Porcelli, F., Lewin, J. L., Cramer, C. & Veglia, G., Apr 1 2006, In : Journal of Organometallic Chemistry. 691, 8, p. 1748-1755 8 p.

Research output: Contribution to journalReview article

Organotin Compounds
Dealkylation
thiols
reactivity
chemistry
36 Citations (Scopus)

Functional and structural properties of stannin: Roles in cellular growth, selective toxicity, and mitochondrial responses to injury

Billingsley, M. L., Yun, J., Reese, B. E., Davidson, C. E., Buck-Koehntop, B. A. & Veglia, G., May 15 2006, In : Journal of Cellular Biochemistry. 98, 2, p. 243-250 8 p.

Research output: Contribution to journalReview article

Toxicity
Structural properties
Wounds and Injuries
Growth
Proteins
2004
17 Citations (Scopus)

Biophysical analyses of designed and selected mutants of protocatechuate 3,4-dioxygenase

Brown, C. K., Vetting, M. W., Earhart, C. A. & Ohlendorf, D. H., Dec 7 2004, In : Annual Review of Microbiology. 58, p. 555-585 31 p.

Research output: Contribution to journalReview article

Protocatechuate-3,4-Dioxygenase
Dioxygenases
Enzymes
Carbon
Iron
2003
3 Citations (Scopus)

Designing βpep peptides: A rational approach to the discovery of novel pharmaceutical agents and small molecules

Mayo, K. H. & Griffioen, A. W., Apr 1 2003, In : Drugs of the Future. 28, 4, p. 337-346 10 p.

Research output: Contribution to journalReview article

Peptides
Pharmaceutical Preparations
Protein Folding
Drug Discovery
Structure-Activity Relationship
17 Citations (Scopus)

Discovery and development of anti-angiogenic peptides: A structural link

Dings, R. P. M., Nesmelova, I., Griffioen, A. W. & Mayo, K. H., Dec 1 2003, In : Angiogenesis. 6, 2, p. 83-91 9 p.

Research output: Contribution to journalReview article

Angiogenic Proteins
Peptide Fragments
Angiogenesis Inhibitors
Tumors
Neoplasms
56 Citations (Scopus)

Glycerol facilitator GlpF and the associated aquaporin family of channels

Stroud, R. M., Miercke, L. J. W., O'Connell, J., Khademi, S., Lee, J. K., Remis, J., Harries, W., Robles, Y. & Akhavan, D., Aug 1 2003, In : Current Opinion in Structural Biology. 13, 4, p. 424-431 8 p.

Research output: Contribution to journalReview article

Aquaporins
Glycerol
Hydrogen
Water
Aquaglyceroporins
17 Citations (Scopus)

The future for antibiotics: Bacterial membrane disintegrators

Lockwood, N. A. & Mayo, K. H., Sep 1 2003, In : Drugs of the Future. 28, 9, p. 911-923 13 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Membranes
Peptides
Genetic Selection
Enzymes
2002
26 Citations (Scopus)

Changes in actin and myosin structural dynamics due to their weak and strong interactions.

Thomas, D. D., Prochniewicz-Nakayama, E. & Roopnarine, O., Jan 1 2002, In : Results and Problems in Cell Differentiation. 36, p. 7-19 13 p.

Research output: Contribution to journalReview article

Myosins
Actins
Nucleotides
Actomyosin
Adenosine Diphosphate
66 Citations (Scopus)

Structural biology of metal-binding sequences

Opella, S. J., DeSilva, T. M. & Veglia, G., Apr 1 2002, In : Current opinion in chemical biology. 6, 2, p. 217-223 7 p.

Research output: Contribution to journalReview article

Metal ions
Metals
Extended X ray absorption fine structure spectroscopy
X ray crystallography
X Ray Crystallography
2001
19 Citations (Scopus)

Angiostatic proteins and peptides

Bouma-ter Steege, J. C. A., Mayo, K. H. & Griffioen, A. W., Dec 1 2001, In : Critical Reviews in Eukaryotic Gene Expression. 11, 4, p. 319-333 15 p.

Research output: Contribution to journalReview article

Angiostatic Proteins
Pathology
Physiological Phenomena
Angiogenesis Inhibitors
Diabetic Retinopathy
2000
13 Citations (Scopus)

Electron transfer and radical forming reactions of methane monooxygenase.

Brazeau, B. J. & Lipscomb, J. D., Jan 1 2000, In : Sub-Cellular Biochemistry. 35, p. 233-277 45 p.

Research output: Contribution to journalReview article

methane monooxygenase
Oxygenases
X ray crystallography
Oxygen
Electrons
1998
21 Citations (Scopus)

Angiogenesis, a target for tumor therapy

Griffioen, A. W., Barendsz-Janson, A. F., Mayo, K. H. & Hillen, H. F. P., Nov 1998, In : Journal of Laboratory and Clinical Medicine. 132, 5, p. 363-368 6 p.

Research output: Contribution to journalReview article

Neoplasms
Therapeutics
60 Citations (Scopus)

MMO: P450 in wolf's clothing?

Lipscomb, J. D. & Que, L., Jun 1 1998, In : Journal of Biological Inorganic Chemistry. 3, 3, p. 331-336 6 p.

Research output: Contribution to journalReview article

methane monooxygenase
Clothing
Hydrocarbons
Mixed Function Oxygenases
Cytochrome P-450 Enzyme System
73 Citations (Scopus)

NMR spectroscopic studies of I = 1/2 metal ions in biological systems

Öz, G., Pountney, D. L. & Armitage, I. M., Dec 1 1998, In : Biochemistry and Cell Biology. 76, 2-3, p. 223-234 12 p.

Research output: Contribution to journalReview article

Biological systems
Metal ions
Metals
Nuclear magnetic resonance
Ions
1994
319 Citations (Scopus)

Biochemistry of the soluble methane monooxygenase

Lipscomb, J. D., Jan 1 1994, In : Annual Review of Microbiology. 48, p. 371-399 29 p.

Research output: Contribution to journalReview article

methane monooxygenase
Catalysis
Biochemistry
NAD
Diagnostic Uses of Chemicals