Chemical and Structural Biology (BMBB)

Fingerprint Dive into the research topics where Chemical and Structural Biology (BMBB) is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

DNA Medicine & Life Sciences
Thymine DNA Glycosylase Medicine & Life Sciences
Proteins Medicine & Life Sciences
HIV-1 Medicine & Life Sciences
Nucleic Acids Medicine & Life Sciences
Nucleocapsid Proteins Medicine & Life Sciences
Single-Stranded DNA Medicine & Life Sciences
Integrases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Kellie S Agrimson

Kellie S Agrimson

Person: Professional-in-Training

No photo of Hideki Aihara

Hideki Aihara

Person: Faculty, Medical School Affiliate

19962024
No photo of Sophie Altamirano

Sophie Altamirano

Person: Professional-in-Training

Projects 1999 2024

APOBEC MUTAGENESIS IN BREAST CANCER

Harris, R., Aihara, H., Harki, D. A., Largaespada, D. A. & Yee, D.

NIH NATIONAL CANCER INSTITUTE (NCI)

8/9/19 → 7/31/24

Project: Research project

Mutagenesis
Breast Neoplasms

Discovery and development of novel anti-HCMV agents targeting the UL89 terminase protein

Geraghty, R. J., Aihara, H., Wang, Z. & Xie, J.

NIH Nat'l Inst of Allergy & Infect Dis

1/25/19 → 12/31/23

Project: Research project

Proteins
terminase

Targeting eIF4A1-dependent HK2 translation axis for prevention of castration-resistant prostate cancer

Deng, Y., Aihara, H., Bhat, M. S., Murugan, P. & Zhang, L.

NIH NATIONAL CANCER INSTITUTE (NCI)

12/1/18 → 11/30/23

Project: Research project

Castration
Prostatic Neoplasms

Research Output 1990 2019

Cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis

Shi, K., Cho, S., Aukema, K. G., Lee, T., Bera, A. K., Seffernick, J. L., Wackett, L. P. & Aihara, H., Jun 2019, In : PloS one. 14, 6, e0216979.

Research output: Contribution to journal › Article

Open Access
Hydrolases
hydrolases
Catalysis
catalytic activity
acids
4 Citations (Scopus)

Determinants of Oligonucleotide Selectivity of APOBEC3B

Wagner, J. R., Demir, Ö., Carpenter, M. A., Aihara, H., Harki, D. A., Harris, R. & Amaro, R. E., May 28 2019, In : Journal of Chemical Information and Modeling. 59, 5, p. 2264-2273 10 p.

Research output: Contribution to journal › Article

Oligonucleotides
Binding sites
DNA
Binding Sites
determinants
6 Citations (Scopus)

Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway

Koehn, E. M., Latham, J. A., Armand, T., Evans, R. L., Tu, X., Wilmot, C. M., Iavarone, A. T. & Klinman, J. P., Mar 13 2019, In : Journal of the American Chemical Society. 141, 10, p. 4398-4405 8 p.

Research output: Contribution to journal › Article

PQQ Cofactor
Biosynthesis
Biosynthetic Pathways
Mixed Function Oxygenases
Iron