Projects per year
Fingerprint Dive into the research topics where Chemical and Structural Biology (BMBB) is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
DNA
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Thymine DNA Glycosylase
Medicine & Life Sciences
Nucleic Acids
Medicine & Life Sciences
Nucleocapsid Proteins
Medicine & Life Sciences
Single-Stranded DNA
Medicine & Life Sciences
HIV-1
Medicine & Life Sciences
Nucleic Acid Denaturation
Medicine & Life Sciences
Network
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Profiles
Kellie S Agrimson
- Chemical and Structural Biology (BMBB) - Post-Doctoral Associate
Person: Professional-in-Training
Sophie Altamirano
- Chemical and Structural Biology (BMBB) - Post-Doctoral Associate
Person: Professional-in-Training
Projects 1999 2023
Discovery and development of novel anti-HCMV agents targeting the UL89 terminase protein
Geraghty, R. J., Aihara, H., Wang, Z. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
1/25/19 → 12/31/23
Project: Research project
Proteins
terminase
Targeting eIF4A1-dependent HK2 translation axis for prevention of castration-resistant prostate cancer
Deng, Y., Aihara, H., Bhat, M. S., Murugan, P. & Zhang, L.
NIH NATIONAL CANCER INSTITUTE (NCI)
12/1/18 → 11/30/23
Project: Research project
Castration
Prostatic Neoplasms
Development and characterization of peptidomimetic small molecule activators of peptidase neurolysin for stroke therapy.
9/15/18 → 8/31/23
Project: Research project
neurolysin
Peptidomimetics
Peptide Hydrolases
Stroke
Therapeutics
Research Output 1991 2019
Cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis
Shi, K., Cho, S., Aukema, K. G., Lee, T., Bera, A. K., Seffernick, J. L., Wackett, L. P. & Aihara, H., Jun 1 2019, In : PloS one. 14, 6, e0216979.Research output: Contribution to journal › Article
Open Access
Hydrolases
hydrolases
Catalysis
catalytic activity
acids
3
Citations
(Scopus)
Determinants of Oligonucleotide Selectivity of APOBEC3B
Wagner, J. R., Demir, Ö., Carpenter, M. A., Aihara, H., Harki, D. A., Harris, R. & Amaro, R. E., May 28 2019, In : Journal of Chemical Information and Modeling. 59, 5, p. 2264-2273 10 p.Research output: Contribution to journal › Article
Oligonucleotides
Binding sites
DNA
Binding Sites
determinants
3
Citations
(Scopus)
Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway
Koehn, E. M., Latham, J. A., Armand, T., Evans, R. L., Tu, X., Wilmot, C. M., Iavarone, A. T. & Klinman, J. P., Mar 13 2019, In : Journal of the American Chemical Society. 141, 10, p. 4398-4405 8 p.Research output: Contribution to journal › Article
PQQ Cofactor
Biosynthesis
Biosynthetic Pathways
Mixed Function Oxygenases
Iron