Organization profile

Organization profile

The mission of the Center for Translational Medicine is to support the development of novel, investigator-initiated treatment strategies in order to facilitate the implementation of new therapies for patients and achieve new breakthroughs in medicine at the University. The Center has a well-equipped lab and a full-time staff and provides the infrastructure, expertise and resources necessary to translate innovative drugs, biological reagents and devices into Phase 1 clinical trials.  Working with innovators from across the University, the Center designs and conducts the preclinical studies necessary for IND/IDE development and supports Phase I clinical trial design and implementation, including manufacture of clinical product.

 

Fingerprint Dive into the research topics where Center for Translational Medicine is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Chemokine CCL2 Medicine & Life Sciences
Cartilage Medicine & Life Sciences
Arthritis Medicine & Life Sciences
Matrix Metalloproteinase 3 Medicine & Life Sciences
Interleukin-1 Medicine & Life Sciences
Chondrocytes Medicine & Life Sciences
Biguanides Medicine & Life Sciences
Complement Membrane Attack Complex Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Lia G Coicou

Lia G Coicou

Person: Researcher

No photo of Craig M Flory

Craig M Flory

Person: Researcher

19892019
No photo of Brenda Koniar

Brenda Koniar

Person: Research Support

Projects 2019 2022

Research Output 1991 2019

2 Citations (Scopus)

In vivo activity and low toxicity of the second-generation antimicrobial peptide DGL13K

Gorr, S. U., Flory, C. M. & Schumacher, R. J., May 1 2019, In : PloS one. 14, 5, e0216669.

Research output: Contribution to journalArticle

Open Access
antimicrobial peptides
Galleria mellonella
Toxicity
peptides
toxicity
1 Citation (Scopus)

Novel N-1 substituted fluoroquinolones inhibit human topoisomerase I activity and exhibit anti-proliferative activity

Oppegard, L. M., Delgado, J. L., Kulkarni, C. A., Towle, T. R., Hart, D. E., Williams, B. P., Lentz, S. R. C., Norris, B., Flory, C. M., Schumacher, R. J., Murry, D. J., Kerns, R. J. & Hiasa, H., Apr 15 2019, In : Investigational New Drugs. 37, 2, p. 378-383 6 p.

Research output: Contribution to journalArticle

Open Access
Type I DNA Topoisomerase
Fluoroquinolones
Heterografts
Human Activities
Poisoning
20 Citations (Scopus)

A completely biological "off-the-shelf" arteriovenous graft that recellularizes in baboons

Syedain, Z. H., Graham, M. L., Dunn, T. B., O'Brien, T. D., Johnson, S. L., Schumacher, R. J. & Tranquillo, R. T., Nov 1 2017, In : Science Translational Medicine. 9, 414, eaan4209.

Research output: Contribution to journalArticle

Papio
Transplants
Renal Dialysis
Veins
Head