Center for Translational Medicine

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Chemokine CCL2 Medicine & Life Sciences
Arthritis Medicine & Life Sciences
Lung Medicine & Life Sciences
Oncorhynchus mykiss Medicine & Life Sciences
Monocytes Medicine & Life Sciences
Interleukin-1 Medicine & Life Sciences
Matrix Metalloproteinase 3 Medicine & Life Sciences
Intercellular Adhesion Molecule-1 Medicine & Life Sciences

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Profiles

No photo of Lia G Coicou

Lia G Coicou

Person: Researcher

No photo of Craig M Flory

Craig M Flory

Person: Researcher

19892017
No photo of Brenda Koniar

Brenda Koniar

Person: Research Support

Research Output 1989 2017

2 Citations (Scopus)

Erratum: Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria (Cell Chemical Biology (2017) 24(10) (1259–1275.e6) (S2451945617302830)(10.1016/j.chembiol.2017.08.009))

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, 1 p.

Research output: Contribution to journal › Comment/debate

Biguanides
Mitochondria
Heme
Cytochrome P-450 Enzyme System
Cell Biology
2 Citations (Scopus)

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journal › Article

Biguanides
Cytochrome P-450 CYP3A
Mitochondria
Heme
Cytochrome P-450 Enzyme System
49 Citations (Scopus)

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis

Jüngel, A., Ospelt, C., Lesch, M., Thiel, M., Sunyer, T., Schorr, O., Michel, B. A., Gay, R. E., Kolling, C., Flory, C., Gay, S. & Neidhart, M., May 1 2010, In : Annals of the Rheumatic Diseases. 69, 5, p. 898-902 5 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 13
Matrix Metalloproteinase Inhibitors
Cartilage
Rheumatoid Arthritis
Animals