Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Chemokine CCL2 Medicine & Life Sciences
Lung Medicine & Life Sciences
Monocytes Medicine & Life Sciences
Messenger RNA Medicine & Life Sciences
Arthritis Medicine & Life Sciences
Oncorhynchus mykiss Medicine & Life Sciences
Cartilage Medicine & Life Sciences
Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1989 2017

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z. , Sevrioukova, I. F. , Denisov, I. G. , Zhang, X. , Chiu, T. L. , Thomas, D. G. , Hanse, E. A. , Cuellar, R. A. D. , Grinkova, Y. V. , Langenfeld, V. W. , Swedien, D. S. , Stamschror, J. D. , Alvarez, J. , Luna, F. , Galván, A. , Bae, Y. K. , Wulfkuhle, J. D. , Gallagher, R. I. , Petricoin, E. F. , Norris, B. & 17 others Flory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A. Oct 19 2017 In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Research - peer-reviewArticle

Biguanides
Cytochrome P-450 CYP3A
Heme
Cytochrome P-450 Enzyme System
Mitochondria

Reply

Flory, C. M. Apr 1 2008 In : Arthritis and Rheumatism. 58, 4, 1 p.

Research output: Research - peer-reviewLetter

32 Citations

PD-0200347, an α2δ ligand of the voltage gated calcium channel, inhibits in vivo activation of the Erk1/2 pathway in osteoarthritic chondrocytes: A PKCα dependent effect

Boileau, C., Martel-Pelletier, J., Brunet, J., Schrier, D., Flory, C., Boily, M. & Pelletier, J. P. May 1 2006 In : Annals of the Rheumatic Diseases. 65, 5, p. 573-580 8 p.

Research output: Research - peer-reviewArticle

Calcium Channels
Chemical activation
Ligands
Electric potential
PD-0200347