Projects per year
Organization profile
Organization profile
The Center for Metabolomics and Proteomics (CMSP) facility provides support to the life sciences research community at the University of Minnesota. As a subunit of the Department of Biochemistry, Molecular Biology and Biophysics (BMBB), the CMSP provides expertise, equipment, training, and support for analyzing all types of biological molecules - with a focus on proteomic and metabolomic applications. With years of experience serving the entire biological science area of the University, the CMSP staff has a wide range of expertise in analytical methods used to characterize a broad range of molecule types. In addition to large-scale discovery studies, CMSP offers targeted mass spectrometry-based methods to characterize proteins, metabolites or other biological molecules of interest.
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Collaborations and top research areas from the last five years
Profiles
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Yue Chen
- Center for Metabolomics and Proteomics - Associate Professor
- Biochemistry, Molecular Biology, and Biophysics (TMED) - Associate Professor
- Carcinogenesis and Chemoprevention
Person: Member, Faculty, Medical School Affiliates
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Timothy J Griffin
- Metabolic and Systems Biology (TMED) - Professor
- Center for Metabolomics and Proteomics - Faculty Director
- Genetics Mechanisms of Cancer
Person: Member, Faculty
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Functional Dissection of Metabolic-Sensing Proline Hydroxylation Pathways
Chen, Y. (PI)
NIH NIGMS NATL INST OF GENERAL
2/1/23 → 1/31/29
Project: Research project
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Dynamics of protein kinase CK2 signaling in prostate cancer pathogenesis Requirement title: Ahmed BLRD 2021-2024 Proteomics Service
Guerrero, C. R. (PI)
U.S. DEPARTMENT OF VETERANS AFFAIRS
8/19/22 → 8/18/25
Project: Research project
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Mechanisms of immunoproteasome-mediated metabolic disorders
Kim, D.-H. (PI) & Chen, Y. (CoI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
5/1/20 → 4/30/25
Project: Research project
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An integrated metaproteomics workflow for studying host-microbe dynamics in bronchoalveolar lavage samples applied to cystic fibrosis disease
Kruk, M. E., Mehta, S., Murray, K., Higgins, L. A., Do, K., Johnson, J. E., Wagner, R., Wendt, C. H., O’Connor, J. B., Harris, J. K., Laguna, T. A., Jagtap, P. D. & Griffin, T. J., Jul 2024, In: mSystems. 9, 7Research output: Contribution to journal › Article › peer-review
Open Access -
A novel clinical metaproteomics workflow enables bioinformatic analysis of host-microbe dynamics in disease
Do, K., Mehta, S., Wagner, R., Bhuming, D., Rajczewski, A. T., Skubitz, A. P. N., Johnson, J. E., Griffin, T. J. & Jagtap, P. D., Jun 2024, In: mSphere. 9, 6Research output: Contribution to journal › Article › peer-review
Open Access -
Improved detection of DNA replication fork-associated proteins
Rivard, R. S., Chang, Y. C., Ragland, R. L., Thu, Y. M., Kassab, M., Mandal, R. S., Van Riper, S. K., Kulej, K., Higgins, L. A., Markowski, T. M., Shang, D., Hedberg, J., Erber, L., Garcia, B., Chen, Y., Bielinsky, A. K. & Brown, E. J., May 28 2024, In: Cell reports. 43, 5, 114178.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
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Data for manuscript, "An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples"
Weise, D. O., Kruk, M., Higgins, L., Markowski, T. W., Jagtap, P. D., Mehta, S., Mickelson, A., Parker, L. L., Wendt, C. H. & Griffin, T. J., ZENODO, Oct 7 2022
DOI: 10.5281/zenodo.7153029, https://zenodo.org/record/7153029
Dataset