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2020

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 3869.

Research output: Contribution to journalArticle

Open Access

Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27

Wang, X., Hennig, T., Whisnant, A. W., Erhard, F., Prusty, B. K., Friedel, C. C., Forouzmand, E., Hu, W., Erber, L., Chen, Y., Sandri-Goldin, R. M., Dölken, L. & Shi, Y., Dec 1 2020, In : Nature communications. 11, 1, 293.

Research output: Contribution to journalArticle

Open Access
2019

A Quantitative Chemical Proteomics Approach for Site-specific Stoichiometry Analysis of Ubiquitination

Li, Y., Evers, J., Luo, A., Erber, L., Postler, Z. & Chen, Y., Jan 8 2019, In : Angewandte Chemie - International Edition. 58, 2, p. 537-541 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
1 Scopus citations

Dentin Priming with Amphipathic Antimicrobial Peptides

Moussa, D. G., Kirihara, J. A., Ye, Z., Fischer, N. G., Khot, J., Witthuhn, B. A. & Aparicio, C., Sep 1 2019, In : Journal of dental research. 98, 10, p. 1112-1121 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Distinct cancer-promoting stromal gene expression depending on lung function

Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S., Higgins, L. A., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B., Wendt, C. H. & Larsson, O., Aug 1 2019, In : American journal of respiratory and critical care medicine. 200, 3, p. 348-358 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism

Lindsay, A., Chamberlain, C. M., Witthuhn, B. A., Lowe, D. A. & Ervasti, J. M., Jan 1 2019, In : Human molecular genetics. 28, 6, p. 942-951 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming to Promote Cell Survival

Noel, B. M., Ouellette, S. B., Marholz, L., Dickey, D., Navis, C., Yang, T. Y., Nguyen, V., Parker, S. J., Bernlohr, D., Sachs, Z. & Parker, L. L., Apr 5 2019, In : Journal of Proteome Research. 18, 4, p. 1842-1856 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Quantifying Intranasally Administered Deferoxamine in Rat Brain Tissue with Mass Spectrometry

Kosyakovsky, J., Witthuhn, B. A., Svitak, A. L., Frey, W. H., Hanson, L. R. & Fine, J. M., Nov 20 2019, In : ACS Chemical Neuroscience. 10, 11, p. 4571-4578 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells

Brian, B. F., Jolicoeur, A. S., Guerrero, C. R., Nunez, M. G., Sychev, Z. E., Hegre, S. A., Sætrom, P., Habib, N., Drake, J. M., Schwertfeger, K. L. & Freedman, T. S., Jul 2019, In : eLife. 8, e46043.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

A role for monomethylation of histone H3-K27 in gene activity in Drosophila

Wang, L., Joshi, P., Miller, E. L., Higgins, L., Slattery, M. & Simon, J. A., Mar 2018, In : Genetics. 208, 3, p. 1023-1036 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
7 Scopus citations
6 Scopus citations

Characterization and metabolic synthetic lethal testing in a new model of SDH-loss familial pheochromocytoma and paraganglioma

Smestad, J., Hamidi, O., Wang, L., Holte, M. N., Al Khazal, F., Erber, L., Chen, Y. & Maher, L. J., Jan 1 2018, In : Oncotarget. 9, 5, p. 6109-6127 19 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism

Smestad, J., Erber, L., Chen, Y. & Maher, L. J., Apr 27 2018, In : iScience. 2, p. 63-75 13 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs

Wendt, C. H., Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S. V., Higgins, L., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B. & Larsson, O., Dec 1 2018, In : Annals of the American Thoracic Society. 15, 4, p. S290-S291

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cold argon-oxygen plasma species oxidize and disintegrate capsid protein of feline calicivirus

Aboubakr, H. A., Mor, S. K., Higgins, L. A., Armien, A., Youssef, M. M., Bruggeman, P. J. & Goyal, S. M., Mar 2018, In : PLoS One. 13, 3, e0194618.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Multi-omic molecular profiling of lung cancer in COPD

Sandri, B. J., Kaplan, A., Hodgson, S. W., Peterson, M., Avdulov, S. V., Higgins, L., Markowski, T., Yang, P., Limper, A. H., Griffin, T. J., Bitterman, P. B., Lock, E. & Wendt, C. H., Jul 1 2018, In : European Respiratory Journal. 52, 1, 1702665.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

Brumbaugh, J., Di Stefano, B., Wang, X., Borkent, M., Forouzmand, E., Clowers, K. J., Ji, F., Schwarz, B. A., Kalocsay, M., Elledge, S. J., Chen, Y., Sadreyev, R. I., Gygi, S. P., Hu, G., Shi, Y. & Hochedlinger, K., Jan 11 2018, In : Cell. 172, 1-2, p. 106-120.e21

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins

Hauck, A. K., Zhou, T., Hahn, W., Petegrosso, R., Kuang, R., Chen, Y. & Bernlohr, D. A., Aug 31 2018, In : Journal of Biological Chemistry. 293, 35, p. 13464-13476 13 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Salivary proteomics of healthy dogs: An in depth catalog

Torres, S. M. F., Furrow, E., Souza, C. P., Granick, J. L., De Jong, E. P., Griffin, T. J. & Wang, X., Jan 2018, In : PloS one. 13, 1, e0191307.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Park, J. M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. A. & Kim, D. H., Apr 3 2018, In : Autophagy. 14, 4, p. 584-597 14 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

ZNF121 interacts with ZBRK1 and BRCA1 to regulate their target genes in mammary epithelial cells

Luo, A., Zhang, K., Zhao, Y., Zhu, Z., Fu, L. & Dong, J. T., Dec 2018, In : FEBS Open Bio. 8, 12, p. 1943-1952 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2017

N6-methyladenine is an epigenetic marker of mammalian early life stress

Kigar, S. L., Chang, L., Guerrero, C. R., Sehring, J. R., Cuarenta, A., Parker, L. L., Bakshi, V. P. & Auger, A. P., Dec 1 2017, In : Scientific reports. 7, 1, 18078.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
Open Access
6 Scopus citations
2016
Open Access
10 Scopus citations
4 Scopus citations

Glucose starvation alters heat shock response, leading to death of wild type cells and survival of MAP kinase signaling mutant

Plesofsky, N., Higgins, L. A., Markowski, T. & Brambl, R., Nov 2016, In : PloS one. 11, 11, e0165980.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Mosaic composition of ribA and wspB genes flanking the virB8-D4 operon in the Wolbachia supergroup B-strain, wStr

Baldridge, G. D., Li, Y. G., Witthuhn, B. A., Higgins, L. A., Markowski, T. W., Baldridge, A. S. & Fallon, A. M., Jan 1 2016, In : Archives of Microbiology. 198, 1, p. 53-69 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Peptides in bronchoalveolar lavage in chronic obstructive pulmonary disease

Wendt, C. H., Nelsestuen, G., Harvey, S., Gulcev, M., Stone, M. & Reilly, C., May 1 2016, In : PloS one. 11, 5, e0155724.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
Open Access
5 Scopus citations

Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells

Zhou, T., Erber, L., Liu, B., Gao, Y., Ruan, H. B. & Chen, Y., Jan 1 2016, In : Oncotarget. 7, 48, p. 79154-79169 16 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Quantitative analysis of the sirt5-regulated lysine succinylation proteome in mammalian cells

Chen, Y., Feb 1 2016, In : Methods in Molecular Biology. 1410, p. 23-37 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

RIPPER: A framework for MS1 only metabolomics and proteomics label-free relative quantification

Van Riper, S. K., Higgins, L., Carlis, J. V. & Griffin, T. J., Jul 1 2016, In : Bioinformatics. 32, 13, p. 2035-2037 3 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Site-Specific Identification of Lysine Acetylation Stoichiometries in Mammalian Cells

Zhou, T., Chung, Y. H., Chen, J. & Chen, Y., Mar 4 2016, In : Journal of Proteome Research. 15, 3, p. 1103-1113 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Slx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic Progression

Thu, Y. M., Van Riper, S. K., Higgins, L. A., Zhang, T., Becker, J. R., Markowski, T. W., Nguyen, H. D., Griffin, T. J. & Bielinsky, A. K., May 10 2016, In : Cell reports. 15, 6, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
Open Access
1 Scopus citations

Tryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease

Gulcev, M., Reilly, C., Griffin, T. J., Broeckling, C. D., Sandri, B. J., Witthuhn, B. A., Hodgson, S. W., Woodruff, P. G. & Wendt, C. H., Sep 29 2016, In : International Journal of COPD. 11, 1, p. 2435-2446 12 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Zinc finger factor ZNF121 is a MYC-interacting protein functionally affecting MYC and cell proliferation in epithelial cells

Luo, A., Zhang, X., Fu, L., Zhu, Z. & Dong, J. T., Dec 20 2016, In : Journal of Genetics and Genomics. 43, 12, p. 677-685 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Genetic analysis and preliminary function study of miR-423 in breast cancer

Zhao, H., Gao, A., Zhang, Z., Tian, R., Luo, A., Li, M., Zhao, D., Fu, L., Fu, L., Dong, J. T. & Zhu, Z., Jun 11 2015, In : Tumor Biology. 36, 6, p. 4763-4771 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
30 Scopus citations

Metaproteomic analysis using the Galaxy framework

Jagtap, P. D., Blakely, A., Murray, K., Stewart, S., Kooren, J., Johnson, J. E., Rhodus, N. L., Rudney, J. & Griffin, T. J., Oct 2015, In : Proteomics. 15, 20, p. 3553-3565 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

PAINS in the assay: Chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS

Dahlin, J. L., Nissink, J. W. M., Strasser, J. M., Francis, S., Higgins, L., Zhou, H., Zhang, Z. & Walters, M. A., Mar 12 2015, In : Journal of medicinal chemistry. 58, 5, p. 2091-2113 23 p.

Research output: Contribution to journalArticle

139 Scopus citations

Sitagliptin Results in a Decrease of Truncated Apolipoprotein C1

Skinner, N. E. B., Wroblewski, M. S., Kirihara, J. A., Nelsestuen, G. L. & Seaquist, E. R., Sep 26 2015, In : Diabetes Therapy. 6, 3, p. 395-401 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Elevated peptides in lung lavage fluid associated with bronchiolitis obliterans syndrome

Stone, M. D., Harvey, S. B., Nelsestuen, G. L., Reilly, C., Hertz, M. I. & Wendt, C. H., Jan 2 2014, In : PloS one. 9, 1, e84471.

Research output: Contribution to journalArticle

2 Scopus citations