Organization profile

Organization profile

The mission of the Center for Genome Engineering (CGE) is to develop and disseminate the tools that enable efficient, responsible genome engineering. At the heart of CGE’s genome engineering technology are transposable elements – segments of DNA capable of changing their chromosomal position or moving from one DNA molecule to another.  Transposable elements constitute a large portion of DNA in many organisms. They naturally shape the genetic code by causing mutations, rearrangements and sequence duplications. CGE scientists are harnessing these naturally occurring genome engineers to enable precise changes to the genetic code.

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    Research Output

    CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells

    Laoharawee, K., Johnson, M. J. & Moriarity, B. S., Feb 1 2020, In : Methods in molecular biology (Clifton, N.J.). 2115, p. 435-444 10 p.

    Research output: Contribution to journalArticle

  • EditR: A Method to Quantify Base Editing from Sanger Sequencing

    Kluesner, M. G., Nedveck, D. A., Lahr, W. S., Garbe, J. R., Abrahante, J. E., Webber, B. R. & Moriarity, B. S., Jun 1 2018, In : The CRISPR journal. 1, p. 239-250 12 p.

    Research output: Contribution to journalArticle